Results 11 to 20 of about 55,045 (229)

SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells

Cell Discovery, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses angiotensin-converting enzyme 2 (ACE2) as a binding receptor to enter cells via clathrin-mediated endocytosis (CME).
Jinliang Wang, Guan Yang, Xinxin Wang, Zhiyuan Wen, Lei Shuai, Jie Luo, Chong Wang, Ziruo Sun, Renqiang Liu, Jinying Ge, Xijun He, Ronghong Hua, Xijun Wang, Xiao Yang, Weiye Chen, Gongxun Zhong, Zhigao Bu   +16 more
doaj   +2 more sources

Age-dependent impairment of metabotropic glutamate receptor 2-dependent long-term depression in the mouse striatum by chronic ethanol exposure. [PDF]

Alcohol, 2020
Johnson KA, Liput DJ, Homanics GE, Lovinger DM.   +3 more
europepmc   +3 more sources

Beyond TFRC: The Pivotal Role of mGluR2 in Feline Calicivirus Entry and Replication [PDF]

Veterinary Sciences
Feline calicivirus (FCV) is among the few members of the Caliciviridae family that can replicate efficiently in vitro. Our recent studies have found the Transferrin Receptor Protein (TFRC) is an entry receptor that facilitates the internalization of FCV.
Ruibin Qi, Hongtao Kang, Yupeng Yang, Kexin Feng, Zhe Liu, Silu Gao, Qian Jiang, Liandong Qu, Jiasen Liu   +8 more
doaj   +2 more sources

Metabotropic glutamate receptor 2 inhibits thalamically-driven glutamate and dopamine release in the dorsal striatum. [PDF]

Neuropharmacology, 2017
Johnson KA, Mateo Y, Lovinger DM.
europepmc   +2 more sources

Molecular determinants of positive allosteric modulation of the human metabotropic glutamate receptor 2. [PDF]

Br J Pharmacol, 2015
Farinha A, Lavreysen H, Peeters L, Russo B, Masure S, Trabanco AA, Cid J, Tresadern G.   +7 more
europepmc   +2 more sources

mGlu2 Receptors in the Basal Ganglia: A New Frontier in Addiction Therapy [PDF]

Frontiers in Bioscience-Landmark
Glutamate is an important neurotransmitter in the mammalian brain. Among the receptors that glutamate interacts with is metabotropic glutamate (mGlu) receptor 2, a Gαi/o-coupled receptor.
Li-Min Mao, Elizabeth Puthumana, John Q. Wang   +2 more
doaj   +2 more sources

Metabotropic Glutamate Receptor 2 Positive Allosteric Modulators: Closing the Gate on Drug Abuse? [PDF]

Biol Psychiatry, 2015
Johnson KA, Lovinger DM.
europepmc   +2 more sources

Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. [PDF]

Proc Natl Acad Sci U S A, 2013
Zhou Z, Karlsson C, Liang T, Xiong W, Kimura M, Tapocik JD, Yuan Q, Barbier E, Feng A, Flanigan M, Augier E, Enoch MA, Hodgkinson CA, Shen PH, Lovinger DM, Edenberg HJ, Heilig M, Goldman D.   +17 more
europepmc   +2 more sources

Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates oestrogen-induced visceral hypersensitivity. [PDF]

Gut, 2015
Cao DY, Bai G, Ji Y, Traub RJ.
europepmc   +2 more sources

Synthesis and preliminary studies of ¹¹C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 2. [PDF]

Theranostics, 2020
Zhang X, Zhang Y, Chen Z, Shao T, Van R, Kumata K, Deng X, Fu H, Yamasaki T, Rong J, Hu K, Hatori A, Xie L, Yu Q, Ye W, Xu H, Sheffler DJ, Cosford NDP, Shao Y, Tang P, Wang L, Zhang MR, Liang SH.   +22 more
europepmc   +2 more sources