EHMTI-0158. Positive allosteric modulators (PAMS) of the metabotropic glutamate receptor 2 (MGLUR2) are effective against nerve injury induced facial allodynia in rats [PDF]
C Horváth+5 more
openalex +1 more source
[ carbonyl - 11 C]4-Fluoro- N -methyl- N -(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([ 11 C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain [PDF]
Jinsoo Hong+9 more
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Probing the lipid environment of the G-protein coupled receptor Metabotropic glutamate receptor 2
The Metabotropic glutamate receptor 2 (mGluR2) belongs to the family of G-protein coupled receptors, a specific class of transmembrane proteins involved in cellular signaling. The functionality of such transmembrane proteins has been identified to largely depend on their microenvironment, namely the lipid bilayer surrounding them.
openaire +2 more sources
Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats [PDF]
J Gao+6 more
openalex +1 more source
Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors [PDF]
Francesco Matrisciano+3 more
openalex +1 more source
Metabotropic Glutamate Receptor 2 Expression Is Chronically Elevated in Male Rats With Post-Traumatic Stress Disorder Related Behavioral Traits Following Repetitive Low-Level Blast Exposure. [PDF]
De Gasperi R+15 more
europepmc +1 more source
Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222. [PDF]
Doornbos ML+9 more
europepmc +1 more source