Results 231 to 240 of about 79,817 (291)

Targeting metabotropic glutamate receptors for symptomatic and disease-modifying treatment in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Alborghetti M, Ceccherelli A, Caridi M, Nicoletti F, Battaglia G, Bruno V.   +5 more
europepmc   +1 more source

Spontaneous partial resolution of autoimmune-mediated brain MRI abnormalities before immunotherapy in anti-metabotropic glutamate receptor 5 encephalitis: a case report. [PDF]

Front Immunol
Chen J, Tang X, Wang L, Guo D, Cao L, Lu K.   +5 more
europepmc   +1 more source

Metabotropic glutamate receptor homo- and heterodimers exhibit distinct responses to orthosteric and allosteric ligands. [PDF]

Mol Pharmacol
McCullock TW, Couch T, Kammermeier PJ.
europepmc   +1 more source

Sleep Deprivation in Rats Causes Dissociation of the Synaptic NMDA Receptor/D1 Dopamine Receptor Heterocomplex. [PDF]

NeuroSci
Kiknadze N, Narmania N, Sepashvili M, Barbakadze T, Zhuravliova E, Shetekauri T, Tkemaladze N, Oniani N, Mikeladze D.   +8 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Cholesterol Localization Around the Metabotropic Glutamate Receptor 2.

The Journal of Physical Chemistry B, 2020
The metabotropic glutamate receptor (mGluR) 2 plays a key role in the central nervous system. mGluR2 has been shown to be regulated by its surrounding lipid environment, especially by cholesterol, by an unknown mechanism.
M. Kurth, Fabio Lolicato, Angélica Sandoval-Pérez, Helman Amaya-Espinosa, Alexander Teslenko, I. Sinning, R. Beck, B. Brügger, Camilo Aponte-Santamaría   +8 more
semanticscholar   +3 more sources

Metabotropic Glutamate Receptor 2 Activators

, 2014
Schizophrenia is a common and severe, often disabling psychiatric illness of unknown aetiology that affects approximately 24 million people worldwide. The illness is characterized by symptomatology comprising positive symptoms (hallucinations and delusional behaviours), negative symptoms (anhedonia, social withdrawal and apathy) and cognitive ...
J. Cid, A. Trabanco, H. Lavreysen
semanticscholar   +2 more sources

Specificity of metabotropic glutamate receptor 2 coupling to G proteins.

Molecular Pharmacology, 2003
Metabotropic glutamate receptor 2 (mGluR2) is a class 3 G protein-coupled receptor and an important mediator of synaptic activity in the central nervous system. Previous work demonstrated that mGluR2 couples to pertussis toxin (PTX)-sensitive G proteins. However, the specificity of mGluR2 coupling to individual members of the G(i/o) family is not known.
P. Kammermeier, Margaret I Davis, S. Ikeda   +2 more
semanticscholar   +3 more sources

Lack of effect of LY314582 (a group 2 metabotropic glutamate receptor agonist) on phencyclidine-induced locomotor activity in metabotropic glutamate receptor 2 knockout mice.

European Journal of Pharmacology, 2000
In metabotropic glutamate receptor 2 (mGlu(2)) knockout mice, the group 2 metabotropic glutamate receptor agonist LY314582 (20 mg/kg, i.p.), a racemate of LY354740, inhibits neither spontaneous nor phencyclidine (PCP)-induced (2.5 mg/kg, s.c.) locomotor activity.
W. P. Spooren, Fabrizio Gasparini, H. Putten, Manuel Koller, Shigetada Nakanishi, Rainer Kuhn   +5 more
semanticscholar   +3 more sources

Positive allosteric modulators of the metabotropic glutamate receptor 2 for the treatment of schizophrenia

Expert Opinion on Therapeutic Patents, 2009
Normalization of excessive glutamate neurotransmission through activation of the metabotropic glutamate receptor 2 (mGluR2) represents a novel and promising approach for the treatment of schizophrenia. This strategy has gained support through the evaluation of dual mGluR2/3 agonists that act directly at the glutamate (orthosteric) binding site ...
M. Fraley
semanticscholar   +3 more sources