BMC Neuroscience, 2008 Background Many studies have focused on the implication of the serotonin and dopamine systems in neuroadaptive responses to the recreational drug 3,4-methylenedioxy-metamphetamine (MDMA).
Malki Rana +3 more
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Oxidative stress and glutamate excretion in alcoholic steatosis: Metabolic synapse between hepatocyte and stellate cell [PDF]
Clinical and Molecular Hepatology, 2020 Chronic alcohol consumption induces the development of alcoholic steatosis in the liver, which is one of the most widespread liver diseases worldwide. During general alcohol metabolism, hepatocytes generate mitochondria- and cytochrome P450 2E1 (CYP2E1 ...
Hee-Hoon Kim +2 more
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Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain
Journal of Biomedical Science, 2009 The antinociceptive effects of honokiol and magnolol, two major bioactive constituents of the bark of Magnolia officinalis, were investigated on animal paw licking responses and thermal hyperalgesia induced by glutamate receptor agonists including ...
Ko Chien-Hsin +4 more
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Astrocyte activation in the anterior cingulate cortex and altered glutamatergic gene expression during paclitaxel-induced neuropathic pain in mice [PDF]
PeerJ, 2015 Spinal astrocyte activation contributes to the pathogenesis of paclitaxel-induced neuropathic pain (PINP) in animal models. We examined glial fibrillary acidic protein (GFAP; an astrocyte marker) immunoreactivity and gene expression of GFAP, glutamate ...
Willias Masocha
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Protocol for interfering peptide injection into adult mouse hippocampus and spatial memory testing
STAR Protocols, 2021 Summary: Metabotropic glutamate receptor-dependent long-term depression (mGluR-LTD) occurs in diverse brain regions and contributes to the plasticity of behavior, learning, and memory. mGluR-LTD relies on rapid (in minutes) local protein synthesis. Here,
Shanshan Cheng +3 more
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Journal of Pharmacological Sciences, 2005 We have investigated whether the intracellular calcium concentration ([Ca2+]i) oscillations induced in astrocytes using the metabotropic glutamate-receptor agonist, (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) are Ca2+-dependent, using ...
Yoshitoku Yoshida +5 more
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Determinants of functional coupling between astrocytes and respiratory neurons in the pre-Bötzinger complex. [PDF]
PLoS ONE, 2011 Respiratory neuronal network activity is thought to require efficient functioning of astrocytes. Here, we analyzed neuron-astrocyte communication in the pre-Bötzinger Complex (preBötC) of rhythmic slice preparations from neonatal mice. In astrocytes that
Christian Schnell +2 more
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NMDA Receptor-Dependent Metaplasticity by High-Frequency Magnetic Stimulation
Neural Plasticity, 2014 High-frequency magnetic stimulation (HFMS) can elicit N-methyl-D-aspartate (NMDA) receptor-dependent long-term potentiation (LTP) at Schaffer collateral-CA1 pyramidal cell synapses.
Tursonjan Tokay +4 more
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Fmr1 deletion enhances and ultimately desensitizes CB1 signaling in autaptic hippocampal neurons
Neurobiology of Disease, 2013 Fragile X Syndrome (FXS) is a heritable form of mental retardation caused by a non-coding trinucleotide expansion of the FMR1 gene leading to loss of expression of this RNA binding protein.
Alex Straiker, Kyung-Tai Min, Ken Mackie
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Conformational rearrangement during activation of a metabotropic glutamate receptor
Nature Chemical Biology, 2020 G protein-coupled receptors (GPCRs) relay information across cell membranes through conformational coupling between the ligand-binding domain and cytoplasmic signaling domain.
B. Liauw, H. S. Afsari, Reza Vafabakhsh
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