Frontiers in Cellular Neuroscience, 2019 BackgroundAstrocytes are now considered as crucial modulators of neuronal synaptic transmission. General anesthetics have been found to inhibit astrocytic activities, but it is not clear whether general anesthetics within the clinical concentration range
Yu Zhang +8 more
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The Metabotropic Glutamate 2/3 Receptor Agonist LY379268 Blocked Nicotine-Induced Increases in Nucleus Accumbens Shell Dopamine only in the Presence of a Nicotine-Associated Context in Rats [PDF]
, 2011 D'Souza, Manoranjan S +4 more
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Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors [PDF]
, 2018 Francesco Matrisciano +7 more
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Could MDMA Promote Stemness Characteristics in Mouse Embryonic Stem Cells via mGlu5 Metabotropic Glutamate Receptors? [PDF]
Cell Journal, 2012 Objective: Ecstasy, or 3, 4 (±) methylenedioxymethamphetamine (MDMA), is a potent neurotoxic drug. One of the mechanisms for its toxicity is the secondary release of glutamate.
Rokhsareh Meamar +4 more
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Broad spectrum proteomics analysis of the inferior colliculus following acute hydrogen sulfide exposure. [PDF]
, 2018 Acute exposure to high concentrations of H2S causes severe brain injury and long-term neurological disorders, but the mechanisms involved are not known.
Anantharam, Poojya +8 more
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Neural Plasticity, 2015 Age-related alterations in the expression of genes and corticostriatal synaptic plasticity were studied in the dorsal striatum of mice of four age groups from young (2-3 months old) to old (18–24 months of age) animals.
Aisa N. Chepkova +2 more
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Targeting of Metabotropic Glutamate Receptors for the Development of Novel Antidepressants
Chronic Stress, 2019 Since discovering that ketamine has robust antidepressant effects, the glutamatergic system has been proposed as an attractive target for the development of novel antidepressants.
Shigeyuki Chaki +2 more
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Increased Metabotropic Glutamate 2/3 Receptor Binding in the Perigenual Anterior Cingulate Cortex of Cloninger Type 2 Alcoholics: A Whole-Hemisphere Autoradiography Study [PDF]
, 2014 Virpi Laukkanen +11 more
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Glutamate Stimulates Local Protein Synthesis in the Axons of Rat Cortical Neurons by Activating α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors and Metabotropic Glutamate Receptors [PDF]
, 2015 Wei-Lun Hsu +7 more
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Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics [PDF]
, 2014 Matosin Natalie +6 more
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