Results 231 to 240 of about 75,386 (292)

Clinical spectrum and outcomes of anti-metabotropic glutamate receptor 5 encephalitis in Chinese patients: a case report and literature review. [PDF]

Front Immunol
Niu Z, Chen S, Wang J, Yu M, Ren J, Liu R, Guo J, Zhang N, Gao F, Hao H.   +9 more
europepmc   +1 more source

Characterizing Spatial Associations Between GluCEST MRI and Neurotransmitter Receptor Density in the Human Cortex. [PDF]

Hum Brain Mapp
Pecsok MK, Shafiei G, Atkins A, Calkins ME, Gur RC, Reddy Nanga RP, Reddy R, Matyi MA, Stifelman J, Robinson H, Baller EB, Shinohara RT, Ruparel K, Linn KA, Wolf DH, Satterthwaite TD, McMillan CT, Roalf D.   +17 more
europepmc   +1 more source

Targeting metabotropic glutamate receptors for symptomatic and disease-modifying treatment in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Alborghetti M, Ceccherelli A, Caridi M, Nicoletti F, Battaglia G, Bruno V.   +5 more
europepmc   +1 more source

Metabotropic glutamate receptor homo- and heterodimers exhibit distinct responses to orthosteric and allosteric ligands. [PDF]

Mol Pharmacol
McCullock TW, Couch T, Kammermeier PJ.
europepmc   +1 more source

Sleep Deprivation in Rats Causes Dissociation of the Synaptic NMDA Receptor/D1 Dopamine Receptor Heterocomplex. [PDF]

NeuroSci
Kiknadze N, Narmania N, Sepashvili M, Barbakadze T, Zhuravliova E, Shetekauri T, Tkemaladze N, Oniani N, Mikeladze D.   +8 more
europepmc   +1 more source

Spontaneous partial resolution of autoimmune-mediated brain MRI abnormalities before immunotherapy in anti-metabotropic glutamate receptor 5 encephalitis: a case report. [PDF]

Front Immunol
Chen J, Tang X, Wang L, Guo D, Cao L, Lu K.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Opportunities and challenges in drug discovery targeting metabotropic glutamate receptor 4

Expert Opinion on Drug Discovery, 2018
Until recently, metabotropic glutamate receptor 4 (mGlu4) has not received adequate attention in terms of drug targeting when compared to other members of the same mGlu receptor family, possibly because of the difficulties encountered in developing highly selective, either orthosteric or allosteric, ligands for this receptor. Areas covered: This review
C. Volpi, F. Fallarino, G. Mondanelli, A. Macchiarulo, U. Grohmann   +4 more
semanticscholar   +3 more sources

Novel metabotropic glutamate receptor 4 and glutamate receptor 8 therapeutics for the treatment of anxiety

Expert Opinion on Investigational Drugs, 2015
The fast actions of the excitatory neurotransmitter glutamate are mediated by glutamate-gated ion channels (ionotropic Glu receptors). Metabotropic glutamate receptors (mGlus) are coupled to second messenger pathways via G proteins and modulate glutamatergic and GABAergic neurotransmission.
J. Raber, R. Duvoisin
semanticscholar   +3 more sources

Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Journal of Medicinal Chemistry, 2011
There is an increasing amount of evidence to support that activation of the metabotropic glutamate receptor 4 (mGlu4 receptor), either with an orthosteric agonist or a positive allosteric modulator (PAM), provides impactful interventions in diseases such as Parkinson's disease, anxiety, and pain.
Sang-phyo Hong, Kevin G. Liu, Gil Ma, M. Sabio, M. Uberti, M. Bacolod, J. Peterson, Z. Zou, A. Robichaud, D. Doller   +9 more
semanticscholar   +3 more sources