Results 181 to 190 of about 55,471 (274)

Negative allosteric modulation of metabotropic glutamate receptor 5 attenuates alcohol self-administration in baboons. [PDF]

Pharmacol Biochem Behav, 2021
Salling MC, Grassetti A, Ferrera VP, Martinez D, Foltin RW.   +4 more
europepmc   +1 more source

A photoswitchable positive allosteric modulator to control the activation of the metabotropic glutamate receptor 5 by light

Anaëlle Dumazer, Roser Borràs‐Tudurí, Iona Truong, Xiaojing Cong, Fanny Malhaire, Xavier Rovira, Xavier Gómez‐Santacana, Laurent Givalois, Guillaume Lebon, Amadeu Llebaria, Cyril Goudet   +10 more
openalex   +1 more source

Relationship between In Vivo Receptor Occupancy and Efficacy of Metabotropic Glutamate Receptor Subtype 5 Allosteric Modulators with Different In Vitro Binding Profiles [PDF]

, 2014
Jerri M. Rook, Mohammed Noor Tantawy, M. Sib Ansari, Andrew S. Felts, Shaun R. Stauffer, Kyle A. Emmitte, Robert Kessler, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn   +11 more
openalex   +1 more source

Tau pathology is associated with postsynaptic metabotropic glutamate receptor 5 (mGluR5) in early Alzheimer's disease in a sex-specific manner. [PDF]

Alzheimers Dement
Wang Y, Wang J, Chen X, Lin Z, You Z, He K, Guo T, Zhao J, Huang Q, Ni R, Guan Y, Li B, Xie F.   +12 more
europepmc   +1 more source

CHPG enhances BDNF and myelination in cuprizone-treated mice through astrocytic metabotropic glutamate receptor 5. [PDF]

Glia, 2021
Saitta KS, Lercher LD, Sainato DM, Patel A, Huang Y, McAuliffe G, Dreyfus CF.   +6 more
europepmc   +1 more source

Generation of monoclonal antibodies against the metabotropic glutamate receptor 5 and progranulin in autoimmune encephalitis and a potential approach to remedy antibody effects

, 2021
Sarah Lina Kurpjuweit
openalex   +2 more sources

Spontaneous partial resolution of autoimmune-mediated brain MRI abnormalities before immunotherapy in anti-metabotropic glutamate receptor 5 encephalitis: a case report. [PDF]

Front Immunol
Chen J, Tang X, Wang L, Guo D, Cao L, Lu K.   +5 more
europepmc   +1 more source

Prevention of L-Dopa-Induced Dyskinesias by MPEP Blockade of Metabotropic Glutamate Receptor 5 Is Associated with Reduced Inflammation in the Brain of Parkinsonian Monkeys. [PDF]

Cells, 2022
Morissette M, Bourque M, Tremblay MÈ, Di Paolo T.   +3 more
europepmc   +1 more source

Pharmacology, Signaling and Therapeutic Potential of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. [PDF]

ACS Pharmacol Transl Sci
Kos JA, Langiu M, Hellyer SD, Gregory KJ.   +3 more
europepmc   +1 more source

Metabotropic Glutamate Receptor 5 as a Potential Biomarker of the Intersection of Trauma and Cannabis Use. [PDF]

Int J Neuropsychopharmacol
Weiss ER, Davis MT, Asch RH, D'Souza DC, Cool R, Esterlis I.   +5 more
europepmc   +1 more source