Results 201 to 210 of about 478,976 (349)

Chronic cocaine enhances release of neuroprotective amino acid taurine: a microdialysis study [PDF]

open access: yes, 2008
Cocaine inhibits high-affinity neurotransmitter uptake at the presynaptic nerve terminals to increase synaptic levels of dopamine, norepinephrine and serotonin^1^. This increase of synaptic dopamine may cause neurotoxicity^2,3^.
Eitan Freedman   +5 more
core   +1 more source

Neural Metabolic Networks: Key Elements of Healthy Brain Function

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
This review originated from the Fourth International Society for Neurochemistry (ISN) and Journal of Neurochemistry (JNC) Flagship School (2022). Here, we describe how the specific bioenergetic profiles and metabolic exchanges between brain cells enable and gate synaptic function and behavior. Then, based on this analysis, we discuss the potential role
Nimrod Madrer   +20 more
wiley   +1 more source

Prenatal Exposure to Lipopolysaccharide or Valproate Leads to Abnormal Accumulation of the NMDA Receptor Agonist D‐Aspartate in the Adolescent Rat Brain

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
Autism spectrum disorder (ASD) is a neurodevelopmental condition linked to glutamatergic neurotransmission abnormalities. We analyzed by HPLC the cerebral and peripheral profiles of D‐aspartate, D‐serine, and other L‐amino acids involved in NMDA receptor signaling in environmental ASD rat models prenatally exposed to lipopolysaccharide or valproate ...
Anna Di Maio   +9 more
wiley   +1 more source

Membrane progesterone and oestrogen receptors modulate GABAergic transmission in the prefrontal cortex of prepubertal male, but not female, mice

open access: yesExperimental Physiology, Volume 110, Issue 6, Page 888-898, 1 June 2025.
Abstract The sex hormones progesterone (P) and oestrogen (E) reorganize GABAergic transmission in the prefrontal cortex (PFC) during the transition from childhood to adolescence, generating a new excitatory–inhibitory balance necessary for the computational capacity of the mature PFC.
Aitana Vázquez‐Sola   +2 more
wiley   +1 more source

Repeated \u3cem\u3eN\u3c/em\u3e-Acetylcysteine Administration Alters Plasticity-Dependent Effects of Cocaine [PDF]

open access: yes, 2007
Cocaine produces a persistent reduction in cystine–glutamate exchange via system xc− in the nucleus accumbens that may contribute to pathological glutamate signaling linked to addiction.
Abdulhameed, Omer   +7 more
core   +1 more source

Differences in Quantification of the Metabotropic Glutamate Receptor 5 Across Bipolar Disorder and Major Depressive Disorder. [PDF]

open access: yesBiol Psychiatry, 2023
Holmes SE   +11 more
europepmc   +1 more source

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