Metabotropic Glutamate 5 Receptor (mGluR5) Antagonists Decrease Nicotine Seeking, But Do Not Affect the Reinforcement Enhancing Effects of Nicotine [PDF]
Matthew I. Palmatier+4 more
openalex +1 more source
Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence
Sophie E. Holmes+11 more
semanticscholar +1 more source
The Enteric Neuronal Circuitry: A Key Ignored Player in Nutrient Sensing Along the Gut–Brain Axis
The enteric nervous system (ENS) regulates critical physiological functions including gut motility, blood flow, and epithelial secretions. Despite its autonomous ability to execute local functions, its communication with the central nervous system is integral to the maintenance of homeostasis.
Ester Nikolla+4 more
wiley +1 more source
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development? [PDF]
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of exquisitely selective drugs. What is
Di Ianni, Mauricio Emiliano+1 more
core +1 more source
Nicotine Use and Metabotropic Glutamate Receptor 5 in Individuals With Major Depressive and Posttraumatic Stress Disorders. [PDF]
Baldassarri SR+6 more
europepmc +1 more source
Design and synthesis of novel heterobiaryl amides as metabotropic glutamate receptor subtype 5 antagonists [PDF]
Santosh S. Kulkarni, Amy Hauck Newman
openalex +1 more source
Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5. [PDF]
Kampen S+10 more
europepmc +1 more source
Genetic ablation of metabotropic glutamate receptor 5 in rats results in an autism-like behavioral phenotype. [PDF]
Eshraghi AA+8 more
europepmc +1 more source
Metabotropic Glutamate Subtype 5 Receptors Are Quantified in the Human Brain with a Novel Radioligand for PET [PDF]
Amira K. Brown+9 more
openalex +1 more source
Spinophilin Limits Metabotropic Glutamate Receptor 5 Scaffolding to the Postsynaptic Density and Cell Type Specifically Mediates Excessive Grooming. [PDF]
Morris CW+9 more
europepmc +1 more source