The C Terminus of the Metabotropic Glutamate Receptor Subtypes 2 and 7 Specifies the Receptor Signaling Pathways [PDF]
, 2001 Julie Perroy +5 more
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Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.ABSTRACT Multiple muscarinic M4 receptor modulators are currently advancing in clinical development for the treatment of positive symptoms in schizophrenia, including agonists and positive allosteric modulators. Considering the importance of comprehending M4 receptor pharmacology for these therapeutic applications, this study investigates M4 receptor ...
Madeleine Merz +5 more
wiley +1 more source
NO ASSOCIATION BETWEEN METABOTROPIC GLUTAMATE RECEPTORS 7 AND 8 (MGLUR7 AND MGLUR8) GENE POLYMORPHISMS AND WITHDRAWAL SEIZURES AND DELIRIUM TREMENS IN ALCOHOL-DEPENDENT INDIVIDUALS [PDF]
, 2002 U. W. Preuss
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Sustainable Food Proteins, Volume 3, Issue 2, June 2025.This comprehensive review highlights the role of taste‐active peptides (TAPs) in modulating food taste and promoting health. It explores the taste profile, structure, sources, interactions with taste receptors, bioactivity, and potential applications of TAPs within the food and nutraceutical industries.
Nesma Elhadad, Jianping Wu
wiley +1 more source
mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS
EMBO Molecular MedicineFragile X syndrome (FXS) is the leading cause of inherited autism and intellectual disabilities. Aberrant protein synthesis due to the loss of fragile X messenger ribonucleoprotein (FMRP) is the major defect in FXS, leading to a plethora of cellular and ...
Vipendra Kumar +6 more
doaj +1 more source
Lack of the metabotropic glutamate receptor subtype 7 selectively modulates Theta rhythm and working memory [PDF]
, 2005 Christian Hölscher +5 more
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Journal of Neurochemistry, Volume 169, Issue 6, June 2025.Autism spectrum disorder (ASD) is a neurodevelopmental condition linked to glutamatergic neurotransmission abnormalities. We analyzed by HPLC the cerebral and peripheral profiles of D‐aspartate, D‐serine, and other L‐amino acids involved in NMDA receptor signaling in environmental ASD rat models prenatally exposed to lipopolysaccharide or valproate ...
Anna Di Maio +9 more
wiley +1 more source
Expression, purification, crystallization and preliminary X-ray analysis of the ligand-binding domain of metabotropic glutamate receptor 7 [PDF]
, 2007 Takanori Muto +3 more
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The Enteric Neuronal Circuitry: A Key Ignored Player in Nutrient Sensing Along the Gut–Brain Axis
The FASEB Journal, Volume 39, Issue 9, 15 May 2025.The enteric nervous system (ENS) regulates critical physiological functions including gut motility, blood flow, and epithelial secretions. Despite its autonomous ability to execute local functions, its communication with the central nervous system is integral to the maintenance of homeostasis.
Ester Nikolla +4 more
wiley +1 more source
Structure–activity relationships in a novel series of 7-substituted-aryl quinolines and 5-substituted-aryl benzothiazoles at the metabotropic glutamate receptor subtype 5 [PDF]
, 2010 Peng Zhang +4 more
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