Results 141 to 150 of about 51,002 (254)

Allosteric activation and genetic antagonism of metabotropic glutamate receptor subtype 7 (mGluR7) : implications for stress-related physiology and behavior [PDF]

, 2006
Kayo Mitsukawa
openalex   +1 more source

Pleiotropic Effects of Grm7/GRM7 in Shaping Neurodevelopmental Pathways and the Neural Substrate of Complex Behaviors and Disorders

Biomolecules
Natural gene variants of metabotropic glutamate receptor subtype 7 (Grm7), coding for mGluR7, affect individuals’ alcohol-drinking preference. Psychopharmacological investigations have suggested that mGluR7 is also involved in responses to cocaine ...
Beatrix M. Gyetvai, Csaba Vadasz
doaj   +1 more source

Delineating the stepwise millisecond allosteric activation mechanism of the class C GPCR dimer mGlu5

Nature Communications
Two-thirds of signaling hormones and one-third of approved drugs exert their effects by binding and modulating the G protein-coupled receptors (GPCRs) activation.
Mingyu Li, Xiaobing Lan, Xinchao Shi, Chunhao Zhu, Xun Lu, Jun Pu, Shaoyong Lu, Jian Zhang   +7 more
doaj   +1 more source

Metabotropic Glutamate Receptor Subtype 7 Ablation Causes Dysregulation of the HPA Axis and Increases Hippocampal BDNF Protein Levels: Implications for Stress-Related Psychiatric Disorders [PDF]

, 2005
Kayo Mitsukawa, Cédric Mombereau, Erika Lötscher, Doncho P. Uzunov, Herman van der Putten, Peter J. Flor, John F. Cryan   +6 more
openalex   +1 more source

Expression, purification, crystallization and preliminary X-ray analysis of the ligand-binding domain of metabotropic glutamate receptor 7 [PDF]

, 2007
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami   +3 more
openalex   +1 more source

Asc-2P Sustains Mitochondrial Glycolysis and Promotes Neural Progenitor Cell Activation via Metabotropic Glutamate Receptor 7 [PDF]

Jian Zhao, Ying Wang, Jing Fang, Ganlu Hu, Kailin Tang, Xianglu Zeng, Changzheng Wang, Yongcun Yu, Tao Zeng, Zhiwei Cao, Guoping Fan   +10 more
openalex   +1 more source

Metabotropic glutamate 7 (mGlu7) receptor: A target for medication development for the treatment of cocaine dependence

, 2012
Xia Li, Zheng‐Xiong Xi, Athina Markou
openalex   +2 more sources

Endocannabinoid signaling modulates neurons of the pedunculopontine nucleus (PPN) via astrocytes. [PDF]

, 2014
The pedunculopontine nucleus (PPN) is known as the cholinergic part of the reticular activating system (RAS) and it plays an important role in transitions of slow-wave sleep to REM sleep and wakefulness.
Antal, Miklós, Bíró, Tamás, Hegyi, Zoltán, Kovács, Adrienn, Kőszeghy, Áron, Pál, Balázs Zoltán, Szücs, Péter, Vincze, János   +7 more
core  

Genome-Wide Detection of Leukemia Biomarkers from lincRNA–Protein-Coding Gene Interaction Networks in the Three-Dimensional Chromatin Structure

Current Issues in Molecular Biology
The human genome is widely transcribed, with part of these transcribed regions producing stably expressed protein-coding or non-coding RNAs. Long intergenic non-coding RNAs (lincRNAs) are significantly differentially expressed in various cell lines and ...
Yue Hou, Wei Ning, Muren Huhe, Chuanjun Shu   +3 more
doaj   +1 more source

Test-retest properties of [11C]PXT012253 as a positron emission tomography (PET) radiotracer in healthy human brain: PET imaging of mGlu4

EJNMMI Research
Background The metabotropic glutamate receptor 4 (mGlu4) has been proposed as a target for Parkinson’s disease to measure levodopa-induced dyskinesia. [11C]PXT012253 is a PET radioligand for mGlu4 (3.4 nM), previously characterized in non-human primates.
Per Stenkrona, Ryosuke Arakawa, Jiamei Guo, Benny Bang-Andersen, Sangram Nag, Mohammad Mahdi Moein, Zhisheng Jia, Zsolt Cselenyi, Christer Halldin, Andrea Varrone   +9 more
doaj   +1 more source