Regulation of metabotropic glutamate receptor 7 (mGluR7) internalization and surface expression by Ser/Thr protein phosphatase 1. [PDF]
J Biol Chem, 2013 Background: mGluR7 is a presynaptic autoreceptor in the CNS, which is regulated by receptor phosphorylation. Results: Protein phosphatase 1 (PP1) binds to mGluR7, promotes Ser-862 dephosphorylation, and increases receptor surface expression.
Suh YH +5 more
europepmc +2 more sources
Pleiotropic Effects of Grm7/GRM7 in Shaping Neurodevelopmental Pathways and the Neural Substrate of Complex Behaviors and Disorders [PDF]
BiomoleculesNatural gene variants of metabotropic glutamate receptor subtype 7 (Grm7), coding for mGluR7, affect individuals’ alcohol-drinking preference. Psychopharmacological investigations have suggested that mGluR7 is also involved in responses to cocaine ...
Beatrix M. Gyetvai, Csaba Vadasz
doaj +2 more sources
Neuropharmacology, 2016 The co-existence of presynaptic G protein coupled receptors, GPCRs, has received little attention, despite the fact that interplay between the signaling pathways activated by such receptors may affect the neurotransmitter release. Using immunocytochemistry and immuhistochemistry we show that mGlu7 and β-adrenergic receptors are co-expressed in a sub ...
J. J. Ferrero +4 more
semanticscholar +4 more sources
Concomitant Deficits in Working Memory and Fear Extinction Are Functionally Dissociated from Reduced Anxiety in Metabotropic Glutamate Receptor 7-Deficient Mice [PDF]
Journal of Neuroscience, 2006 Z. Callaerts-Végh +7 more
semanticscholar +2 more sources
A Novel Connection between Rods and ON Cone Bipolar Cells Revealed by Ectopic Metabotropic Glutamate Receptor 7 (mGluR7) in mGluR6-Deficient Mouse Retinas [PDF]
Journal of Neuroscience, 2007 Y. Tsukamoto +6 more
semanticscholar +2 more sources
Neuroscience, 2011 Recent studies demonstrated that the metabotropic glutamate receptor subtype 7 "mGluR7" activation may reduce motivational aspects of ethanol dependence. We investigated the role of mGlu7 receptor in ethanol-related behaviors using the allosteric agonist AMN082 in mice.
Amine Bahí
openalex +4 more sources
Metabotropic Glutamate Receptor 7 Modulates the Rewarding Effects of Cocaine in Rats: Involvement of a Ventral Pallidal GABAergic Mechanism [PDF]
Neuropsychopharmacology, 2009 Xia Li +5 more
semanticscholar +2 more sources
European Psychiatry, 2023 Introduction Schizophrenia is a neuropsychiatric disorder characterised by positive, negative and cognitive behavioral symptoms. Despite years of research, the need for suitable therapy remains elusive.
R. O. Folarin, O. Owoeye, A. Malomo
doaj +1 more source
Astrocyte activation in the anterior cingulate cortex and altered glutamatergic gene expression during paclitaxel-induced neuropathic pain in mice [PDF]
PeerJ, 2015 Spinal astrocyte activation contributes to the pathogenesis of paclitaxel-induced neuropathic pain (PINP) in animal models. We examined glial fibrillary acidic protein (GFAP; an astrocyte marker) immunoreactivity and gene expression of GFAP, glutamate ...
Willias Masocha
doaj +2 more sources