Results 161 to 170 of about 100,227 (220)
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The metabotropic glutamate receptors: structure and functions.
Neuropharmacology, 1995J. Pin, R. Duvoisin
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Metabotropic glutamate receptors
Pharmacology Biochemistry and Behavior, 2002Abstract Glutamate, like other neurotransmitters (acetylcholine, ATP, serotonine, glycine, GABA), acts on two main types of membrane receptors: ligand-gated channels, also called ionotropic receptors (iGluRs), and G protein coupled receptors also called metabotropic glutamate receptors (mGluRs).
Darryle D Schoepp, P.Jeffrey Conn
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Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
Neuropharmacology, 1999D. Schoepp, D. Jane, J. Monn
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Homer: a protein that selectively binds metabotropic glutamate receptors
Nature, 1997P. Brakeman +6 more
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Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors
Nature, 1997K. Kaupmann +10 more
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Pharmacological Reviews, 2020
Metabotropic glutamate (mGlu) receptors respond to glutamate, the major excitatory neurotransmitter in the mammalian brain, mediating a modulatory role that is critical for higher-order brain functions such as learning and memory.
K. Gregory, C. Goudet
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Metabotropic glutamate (mGlu) receptors respond to glutamate, the major excitatory neurotransmitter in the mammalian brain, mediating a modulatory role that is critical for higher-order brain functions such as learning and memory.
K. Gregory, C. Goudet
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Metabotropic Glutamate Receptors
Amino Acids, 2007l-Glutamate, one of the main neurotransmitters in the central nervous system (CNS), acts on two groups of receptors: (a) a group of ionotropic receptors that includes N-methyl-d-aspartate (NMDA), α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), and kainate receptors, and (2) a group of metabotropic receptors (mGluRs).
A. Pilc, K. Ossowska
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Metabotropic glutamate receptors and epilepsy
Journal of the Neurological Sciences, 2006Metabotropic glutamate receptors (mGluRs) play an important role in the initiation of ictal discharges by participating in the interictal-ictal transition, and may play a crucial role in recruiting normal brain tissue into synchronized discharges, thereby facilitating propagation of seizure activity.
Jorge, Ure +2 more
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Estrogen receptor signaling through metabotropic glutamate receptors
2020As the non-nuclear initiated effects of steroid hormone signaling have become more widely accepted, there has been a need to define the novel mechanisms of hormone receptor action that account for these outcomes. One mechanism that has emerged is the coupling of classical estrogen receptors (ERα and ERβ) with metabotropic glutamate receptors (mGluRs ...
Kellie S, Gross, Paul G, Mermelstein
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Journal of Pharmacology and Experimental Therapeutics, 2001
Metabotropic glutamate (mGlu) receptors, which include mGlu1-8 receptors, are a heterogeneous family of G-protein-coupled receptors which function to modulate brain excitability via presynaptic, postsynaptic and glial mechanisms.
D. Schoepp
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Metabotropic glutamate (mGlu) receptors, which include mGlu1-8 receptors, are a heterogeneous family of G-protein-coupled receptors which function to modulate brain excitability via presynaptic, postsynaptic and glial mechanisms.
D. Schoepp
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