Results 151 to 160 of about 2,336,805 (315)

Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors [PDF]

, 1995
M.T Taber, HC Fibiger
openalex   +1 more source

Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

Science, 2014
Huixian Wu, Chong Wang, K. Gregory, K. Gregory, G. Han, Hyekyung P. Cho, Yao Xia, C. Niswender, V. Katritch, J. Meiler, V. Cherezov, P. Conn, R. Stevens   +12 more
semanticscholar   +1 more source

Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice

Fundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT Anxiety disorders rank among the most prevalent mental health conditions worldwide, significantly affecting patients' lives. They are frequently comorbid with other psychiatric disorders, often exacerbating their severity. Current pharmacological treatments; selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines, remain limited in
Salma R. Abdennebi, Nour El Haya Touihri, Emmanuelle Corruble, Denis J. David, Indira Mendez‐David   +4 more
wiley   +1 more source

Axon/Dendrite Targeting of Metabotropic Glutamate Receptors by Their Cytoplasmic Carboxy-Terminal Domains [PDF]

, 1999
Julia Nash Stowell, Ann Marie Craig
openalex   +1 more source

MGlu5 Dependent Mitochondrial Translocation of PKCδ: A Mechanism Raising Astrocytic Oxidative Metabolism in Response to Extracellular Glutamate

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
The observations suggest a new mechanism, the mGluR5/PKCδ/PDH axis by which extracellular glutamate can raise oxidative metabolism in astrocytes, in response to rapidly increasing energy demands, such as in the liver or skeletal muscle. It appears that the plethora of astrocytic mitochondria maintain only a basal level of oxidative metabolism during ...
Kiavasch M. N. Farid, Rodrigo Lerchundi, Christine R. Rose, Amin Derouiche   +3 more
wiley   +1 more source

Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus [PDF]

, 1996
Domenico E. Pellegrini‐Giampietro, Serenella Albani Torregrossa, Flavio Moroni   +2 more
openalex   +1 more source

Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model

Nature Communications, 2014
Andrea Delekate, Martina Füchtemeier, Toni Schumacher, Cordula Ulbrich, Marco Foddis, G. Petzold   +5 more
semanticscholar   +1 more source

From Neurotransmission to Retinal Pathophysiology: Unraveling the Role of GABA Receptors in Retinal Disease Progression

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
GABA receptors, widely expressed in the retina, play a key role in lateral inhibition and synaptic regulation. Emerging evidence links their dysregulation to retinal diseases such as diabetic retinopathy, retinitis pigmentosa, glaucoma, and age‐related macular degeneration.
Alan E. Medina Arellano, Jesus Silvestre Albert‐Garay, Nadia Flores Huerta, Karla Tovar Hernández, Matilde Ruiz‐Cruz, Lenin Ochoa‐de la Paz   +5 more
wiley   +1 more source

Metabotropic glutamate receptor-initiated translocation of protein kinase p90rsk to polyribosomes: A possible factor regulating synaptic protein synthesis [PDF]

, 1998
Frank Angenstein, William T. Greenough, Ivan Jeanne Weiler   +2 more
openalex   +1 more source

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source