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Differential Epigenetic Regulation of Glutamatergic Synapse Pathway in Adults With Prenatal Exposure to Famine. [PDF]
Tan Z, Li W, Wang W, Zhang D, Tan Q.
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Attenuation of mGluR1/5-dependent synaptic plasticity and ERK pathway dysfunction in the hippocampus of diabetic rats. [PDF]
Otsuka H +3 more
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The Role of Ion Channels and Transporters in Human Health and Diseases. [PDF]
Soda T.
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Targeting Excitatory Glutamate Receptors for Morphine Tolerance: A Narrative Review. [PDF]
Huang M +6 more
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Radiosynthesis and evaluation of an <sup>18</sup>F-labeled radioligand for imaging metabotropic glutamate receptor 3 with positron emission tomography. [PDF]
Rong J +17 more
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Metabotropic glutamate receptors
Cell and Tissue Research, 2006Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
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Metabotropic glutamate receptors
Pharmacology Biochemistry and Behavior, 2002Abstract Glutamate, like other neurotransmitters (acetylcholine, ATP, serotonine, glycine, GABA), acts on two main types of membrane receptors: ligand-gated channels, also called ionotropic receptors (iGluRs), and G protein coupled receptors also called metabotropic glutamate receptors (mGluRs).
Darryle D Schoepp, P.Jeffrey Conn
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Metabotropic glutamate receptors
Amino Acids, 2007l-Glutamate, one of the main neurotransmitters in the central nervous system (CNS), acts on two groups of receptors: (a) a group of ionotropic receptors that includes N-methyl-d-aspartate (NMDA), α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), and kainate receptors, and (2) a group of metabotropic receptors (mGluRs).
A. Pilc, K. Ossowska
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Metabotropic glutamate receptors and epilepsy
Journal of the Neurological Sciences, 2006Metabotropic glutamate receptors (mGluRs) play an important role in the initiation of ictal discharges by participating in the interictal-ictal transition, and may play a crucial role in recruiting normal brain tissue into synchronized discharges, thereby facilitating propagation of seizure activity.
Jorge, Ure +2 more
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