Results 161 to 170 of about 2,328,855 (357)

Sensory receptors – design principles revisited

open access: yesFrontiers in Cellular Neuroscience, 2013
Dieter eWicher
doaj   +1 more source

Hyperhomocysteinemia‐Driven Ischemic Stroke: Unraveling Molecular Mechanisms and Therapeutic Horizons

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
Neurotoxicity of Hcy. (A figure that best represents the scope of the paper.) Homocysteine can reduce the tightness of endothelial cell connections, increase vascular permeability, and damage the blood–brain barrier. Homocysteine activates various glutamate receptors on the surfaces of neurons and glial cells, triggering excitotoxicity, promoting the ...
Bin Li, Yushun Kou, Lingna Zhang, Lin Yi
wiley   +1 more source

Temporal Profiling of Male Cortical Astrocyte Transcription Predicts Molecular Shifts From Early Development to Aging

open access: yesGlia, Volume 73, Issue 7, Page 1349-1364, July 2025.
Main Points Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain.
Xiaoran Wei   +2 more
wiley   +1 more source

Multi‐Omic Analysis Reveals Astrocytic Annexin‐A2 as Critical for Network‐Level Circadian Timekeeping in the Suprachiasmatic Nucleus

open access: yesGlia, Volume 73, Issue 7, Page 1483-1501, July 2025.
Main Points Multi‐omics reveal Annexin‐A2 (A2) and S100a10 (A10) as SCN astrocyte enriched proteins. Disrupting A2‐A10 complex elevates astrocyte Ca2+ and compromises SCN timekeeping. Astrocytic A2‐A10 is a critical control point for SCN network rhythms.
Andrew P. Patton   +6 more
wiley   +1 more source

Chronic α5‐GABA‐A Receptor Potentiation Promotes Mouse Adult Hippocampal Neurogenesis

open access: yesHippocampus, Volume 35, Issue 4, July 2025.
ABSTRACT Several lines of evidence implicate adult hippocampal neurogenesis (AHN) in cognitive functions, in mood‐ and anxiety‐related behaviors, and in the therapeutic effects of antidepressants. Augmenting α5‐γ‐Aminobutyric acid type A (GABAA) receptor function has shown neurotrophic effects in stress and aged models, but its impact on mouse AHN ...
Thomas D. Prevot   +7 more
wiley   +1 more source

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1 [PDF]

open access: hybrid, 1995
C. Joly   +5 more
openalex   +1 more source

Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]

open access: yes, 2001
The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Dr. Ulrich   +1 more
core  

Understanding the Intersection Between Hormonal Dynamics and Brain Plasticity in Alzheimer's Disease: A Narrative Review for Implementing New Therapeutic Strategies

open access: yesHealth Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aims Alzheimer's disease (AD), a chronic neurodegenerative disorder, is portrayed by neurocognitive decline in the structure and function of the human brain. Various factors are implicated in the pathogenesis to neuroplasticity alteration in the brain of an individual afflicted with AD.
Abir Ghosson   +4 more
wiley   +1 more source

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