Results 161 to 170 of about 2,336,805 (315)

Role of metabotropic glutamate receptors in the depression of GABA-mediated depolarization of frog primary afferent terminals

, 1997
J.C. Hackman, Alice M. Holohean, Robert A. Davidoff   +2 more
openalex   +1 more source

Non‐ionotropic NMDAR signalling activates Panx1 to induce P2X4R‐dependent long‐term depression in the hippocampus

The Journal of Physiology, Volume 603, Issue 15, Page 4367-4381, 1 August 2025.
Abstract figure legend Stimulation of the Shaffer collateral pathway at 3 Hz activates non‐ionotropic NMDA receptors. This subsequently leads to Src kinase mediated phosphorylation of pannexin‐1 (Panx1), which releases ATP from the postsynaptic cell. ATP acts as a ligand for P2X4 receptors to induce long‐term depression (LTD). Abstract In recent years,
Allison C. Nielsen, Connor L. Anderson, Carina Ens, Andrew K. J. Boyce, Roger J. Thompson   +4 more
wiley   +1 more source

Structural insights into the activation of metabotropic glutamate receptors

Nature, 2019
A. Koehl, Hongli Hu, D. Feng, Bingfa Sun, Yan Zhang, M. J. Robertson, M. Chu, T. S. Kobilka, T. Laeremans, J. Steyaert, Jeffrey Tarrasch, S. Dutta, R. Fonseca, W. Weis, J. M. Mathiesen, G. Skiniotis, B. Kobilka   +16 more
semanticscholar   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, Volume 603, Issue 15, Page 4237-4253, 1 August 2025.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

LY354740, an agonist of glutamatergic metabotropic receptor mGlu_2/3 increases the cytochrome P450 2D (CYP2D) activity in the frontal cortical area of rat brain. [PDF]

Pharmacol Rep
Bromek E, Haduch A, Pukło R, Daniel WA.
europepmc   +1 more source

Metabotropic glutamate receptor subtypes mediating slow inward tail current (I_ADP) induction and inhibition of synaptic transmission in olfactory cortical neurones [PDF]

, 1997
Vincenzo Libri, Andrew Constanti, Maurizio Zibetti, Michael Postlethwaite   +3 more
openalex   +1 more source

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

Neuron, 2013
J. Um, A. Kaufman, M. Kostylev, J. K. Heiss, M. Stagi, Hideyuki Takahashi, Meghan E. Kerrisk, A. Vortmeyer, T. Wisniewski, A. Koleske, E. C. Gunther, H. Nygaard, S. Strittmatter   +12 more
semanticscholar   +1 more source

Key Grazing Behaviours of Beef Cattle Identify Specific Genotypes of the Glutamate Metabotropic Receptor 5 Gene (GRM5). [PDF]

Behav Genet
Moreno García CA, Perelman SB, Dynes R, Maxwell TMR, Zhou H, Hickford J.   +5 more
europepmc   +1 more source

Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression

Proceedings of the National Academy of Sciences of the United States of America, 2013
S. Nabavi, H. Kessels, Stephanie Alfonso, Jonathan Aow, R. Fox, R. Malinow   +5 more
semanticscholar   +1 more source

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source