Results 161 to 170 of about 2,386,092 (307)

Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence

Proceedings of the National Academy of Sciences of the United States of America, 2017
Sophie E. Holmes, M. Girgenti, Margaret T. Davis, R. Pietrzak, Nicole DellaGioia, N. Nabulsi, D. Matuskey, S. Southwick, R. Duman, R. Carson, J. Krystal, I. Esterlis   +11 more
semanticscholar   +1 more source

Oxytocinergic Signaling in Zebrafish: Translational Perspectives for Autism Spectrum Disorder

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Alterations in oxytocin signaling are strongly implicated in the social and cognitive deficits characterizing Autism Spectrum Disorder (ASD) and other neurodevelopmental conditions. However, the precise mechanisms remain unclear. The zebrafish (Danio rerio) has emerged as a powerful translational model due to its evolutionarily conserved oxytocin ...
Géssica Peres, Melissa Talita Wiprich, Darlan Gusso, Carla Denise Bonan   +3 more
wiley   +1 more source

Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease.

Brain : a journal of neurology, 2016
L. Haas, Santiago V. Salazar, M. Kostylev, J. Um, A. Kaufman, S. Strittmatter   +5 more
semanticscholar   +1 more source

Sevoflurane Inhibits Layer 5 Pyramidal Neurons via Kv1.2‐Dependent Modulation of Subthreshold Currents

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
General anesthetics suppress cortical activity, but their cellular mechanisms remain unclear. We investigated how the volatile anesthetic sevoflurane affects layer 5 pyramidal neurons in the auditory cortex. Using patch‐clamp recordings and computational modeling, we found that low‐dose sevoflurane reduces neuronal firing through Kv1.2 channel ...
Aelton S. Araujo, Gabriel M. de Queiroz, Sérgio Ruschi B. Silva, Werner Treptow, Katarina E. Leao   +4 more
wiley   +1 more source

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira, Robson Xavier Faria, Wei Wang   +2 more
wiley   +1 more source

Anticonvulsant action of metabotropic glutamate receptor agonists in DBA/2 mice.

, 1994
Yoshiko Horikawa, Shigeki Tamura, Norio Inomata, Tomochika Ohno   +3 more
openalex   +1 more source

Axon/Dendrite Targeting of Metabotropic Glutamate Receptors by Their Cytoplasmic Carboxy-Terminal Domains [PDF]

, 1999
Julia Nash Stowell, Ann Marie Craig
openalex   +1 more source

Finely Tuned Gamma Oscillations in the Globus Pallidus Internus in Parkinson's Disease

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 294-296, January 2026.
Hikaru Kamo, Mallory L.S. Eisel, Jackson N. Cagle, Kara A. Johnson, Joshua Wong, Coralie de Hemptinne   +5 more
wiley   +1 more source

Extracellular acidity and ATP modulate ion currents in human cumulus cells indicating possible roles as metabolic sensors of the follicular microenvironment

Physiological Reports, Volume 14, Issue 2, January 2026.
Extracellular acidity and ATP modify electrophysiological profile in human cumulus cell subpopulations, characterized by differential functional expression of TRPM5‐like, BKCa and KV1.5 currents. Abstract Cumulus cells (CCs), derived from granulosa cells, play a key role in supporting oocyte maturation and development through bidirectional ...
Andrea Biagini, Rosaria Gentile, Cristina Corbucci, Monica Mariani, Alessandro Favilli, Sandro Gerli, Bernard Fioretti   +6 more
wiley   +1 more source