Results 161 to 170 of about 2,328,855 (357)
Sensory receptors – design principles revisited
Dieter eWicher
doaj +1 more source
Neurotoxicity of Hcy. (A figure that best represents the scope of the paper.) Homocysteine can reduce the tightness of endothelial cell connections, increase vascular permeability, and damage the blood–brain barrier. Homocysteine activates various glutamate receptors on the surfaces of neurons and glial cells, triggering excitotoxicity, promoting the ...
Bin Li, Yushun Kou, Lingna Zhang, Lin Yi
wiley +1 more source
Main Points Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain.
Xiaoran Wei+2 more
wiley +1 more source
Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1 [PDF]
RW Gereau, P. Jeffrey Conn
openalex +1 more source
Main Points Multi‐omics reveal Annexin‐A2 (A2) and S100a10 (A10) as SCN astrocyte enriched proteins. Disrupting A2‐A10 complex elevates astrocyte Ca2+ and compromises SCN timekeeping. Astrocytic A2‐A10 is a critical control point for SCN network rhythms.
Andrew P. Patton+6 more
wiley +1 more source
Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors [PDF]
M.T Taber, HC Fibiger
openalex +1 more source
Chronic α5‐GABA‐A Receptor Potentiation Promotes Mouse Adult Hippocampal Neurogenesis
ABSTRACT Several lines of evidence implicate adult hippocampal neurogenesis (AHN) in cognitive functions, in mood‐ and anxiety‐related behaviors, and in the therapeutic effects of antidepressants. Augmenting α5‐γ‐Aminobutyric acid type A (GABAA) receptor function has shown neurotrophic effects in stress and aged models, but its impact on mouse AHN ...
Thomas D. Prevot+7 more
wiley +1 more source
Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1 [PDF]
C. Joly+5 more
openalex +1 more source
Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]
The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Dr. Ulrich+1 more
core
ABSTRACT Background and Aims Alzheimer's disease (AD), a chronic neurodegenerative disorder, is portrayed by neurocognitive decline in the structure and function of the human brain. Various factors are implicated in the pathogenesis to neuroplasticity alteration in the brain of an individual afflicted with AD.
Abir Ghosson+4 more
wiley +1 more source