Results 41 to 50 of about 37,318 (237)

A novel combination of triple metachronous malignancies of the kidney, oropharynx and prostate. A case report [PDF]

, 2015
Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza ...
Carbone, Antonio, Leto, Antonino, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Porta, Natale, Silvestri, Luigi   +6 more
core   +1 more source

Metachronous pulmonary and adrenal metastases after liver transplantation for hepatocarcinoma

World Journal of Surgical Oncology, 2011
Background The worldwide experience of surgical resection for isolated metastasis following liver transplantation (LT) for hepatocellular carcinoma (HCC) is limited.
Chen Shan-Wen, Wang Shuo, Wang Bo, Li Wei-Dong, Yan Sheng, Xie Li-Ping   +5 more
doaj   +1 more source

Repeat Next-Generation Sequencing (15-Gene Panel) in Unifocal, Synchronous, and Metachronous Non-Small-Cell Lung Cancer—A Single-Center Experience

Current Oncology
In advanced non-squamous non-small-cell lung cancer (NSCLC), routine testing with next-generation sequencing (NGS) is recommended to identify actionable genomic alterations (AGAs).
Shelley Kuang, Kaitlin Chen, Sachin Sayal, Gajeni Prabahan, Mary R. Rabey, Lisa W. Le, Andrew Seto, Frances A. Shepherd, Geoffrey Liu, Penelope Bradbury, Adrian G. Sacher, Jennifer H. Law, Peter Sabatini, Tracy L. Stockley, Ming S. Tsao, Natasha B. Leighl   +15 more
doaj   +1 more source

A rare case of triple negative synchronous bilateral invasive ductal carcinoma of breast

Archives of Medicine and Health Sciences, 2016
The occurrence of bilateral breast carcinoma is extremely rare with an incidence of 2-5% of all breast malignancies. We hereby report an unusual and interesting case of triple negative synchronous invasive ductal carcinoma (IDC) of bilateral breasts ...
Abhishek Purkayastha, Neelam Sharma, Nishant Lohia   +2 more
doaj   +1 more source

Comparison of prognostic factors that affect the survival of patients with metachronous and synchronous metastases of renal cell carcinoma

Вестник урологии, 2022
Introduction. The differences in progression-free survival (PFS) and overall survival (OS) depending on the line of systemic therapy, the timing of the onset of metastases, and Heng prognostic groups in patients with metastatic renal cell carcinoma (mRCC)
D. V. Semenov, R. V. Orlova, V. I. Shirokorad, S. V. Kostritsky, S. G. Grigoriev, Yu. S. Korneva   +5 more
doaj   +1 more source

MicroRNA-203 predicts human survival after resection of colorectal liver metastasis. [PDF]

, 2016
BackgroundResection of colorectal liver metastasis (CRLM) can be curative. Predicting which patients may benefit from resection, however, remains challenging. Some microRNAs (miRNAs) become deregulated in cancers and contribute to cancer progression.
D'Angelica, Michael I, Goodarzi, Hani, Jarnagin, William R, Kingham, T Peter, Konstantinidis, Ioannis T, Kuk, Deborah, Nguyen, Hoang CB, Sadot, Eran, Saltz, Leonard, Shia, Jinru, Tavazoie, Sohail F, Zhang, Steven, Zheng, Jian   +12 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Illuminating Bilateral Breast Cancer: A Multicenter Experience and Clinical Observations

Medicina
Background and Objectives: Although breast cancer is the most common type of cancer among women, bilateral breast cancer (BBC) remains exceedingly rare. BBC can present as either synchronous (SBBC) or metachronous (MBBC) disease.
Berkan Karabuğa, Mustafa Büyükkör, Ekin Konca Karabuğa, Sedat Yıldız, Mirmehdi Mehtiyev, Havva Yeşil Çınkır, Sıla Soylu Koçoğlu, Hacer Demir, Ozan Yazıcı, Doğan Uncu, Ömür Berna Öksüzoğlu, Ülkü Yalçıntaş Arslan   +11 more
doaj   +1 more source

Genomic homogeneity in fibrolamellar carcinomas [PDF]

, 2001
Background-Fibrolamellar carcinoma (FLC) is a variant of hepatocellular carcinoma (HCC) with distinctive clinical and histological features. To date there have been few studies on the genotypic aspects of FLC and no previous attempts have been made to ...
Davidson, BR, Lemoine, NR, Sirivatanauksorn, V, Sirivatanauksorn, Y, Williamson, RCN   +4 more
core   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source