Results 51 to 60 of about 707,616 (324)

Automatic Metadata Generation using Associative Networks

open access: yes, 2009
In spite of its tremendous value, metadata is generally sparse and incomplete, thereby hampering the effectiveness of digital information services. Many of the existing mechanisms for the automated creation of metadata rely primarily on content analysis ...
de Lin S.   +7 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Publishing trends of journals with manuscripts in PubMed Central: changes from 2008–2009 to 2015–2016

open access: yesJournal of the Medical Library Association, 2018
Objective: The National Institutes of Health (NIH) public access policy mandates that all articles containing NIH-funded research must be deposited into PubMed Central (PMC). The aim of this study was to assess publishing trends of journals that were not
Lauren Topper, Diane Boehr
doaj   +1 more source

The Evolution of Embedding Metadata in Blockchain Transactions [PDF]

open access: yes, 2018
The use of blockchains is growing every day, and their utility has greatly expanded from sending and receiving crypto-coins to smart-contracts and decentralized autonomous organizations.
Courtois, Nicolas   +2 more
core   +2 more sources

Experiences with metadata [PDF]

open access: yes, 1997
Proceedings of the 7th International Symposium on Spatial Data ...
Timpf, Sabine   +2 more
openaire   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Provenance Description of Metadata Vocabularies for the Long-term Maintenance of Metadata

open access: yesJournal of Data and Information Science, 2017
The purpose of this paper is to discuss provenance description of metadata terms and metadata vocabularies as a set of metadata terms. Provenance is crucial information to keep track of changes of metadata terms and metadata vocabularies for their ...
Li Chunqiu, Sugimoto Shigeo
doaj   +1 more source

Sustaining Collection Value: Managing Collection/Item Metadata Relationships [PDF]

open access: yes, 2008
Many aspects of managing collection/item metadata relationships are critical to sustaining collection value over time. Metadata at the collection-level not only provides context for finding, understanding, and using the items in the collection, but is ...
Dubin, David   +4 more
core  

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