Results 51 to 60 of about 733,097 (288)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Provenance Description of Metadata Vocabularies for the Long-term Maintenance of Metadata
Journal of Data and Information Science, 2017 The purpose of this paper is to discuss provenance description of metadata terms and metadata vocabularies as a set of metadata terms. Provenance is crucial information to keep track of changes of metadata terms and metadata vocabularies for their ...
Li Chunqiu, Sugimoto Shigeo
doaj +1 more source
A Metadata Prefetching Strategy Based on Provenance Information [PDF]
Jisuanji gongcheng, 2016 In distributed file systems,metadata prefetching can reduce the response latency of metadata server.Existing metadata prefetching strategies prefetch metadata according to its past file access pattern,without considering the correlations between process ...
WU Guojin,HU Cheng
doaj +1 more source
MoPark Initiative, Metadata Options Appraisal (Phase I) [PDF]
, 2004 Examines – and makes recommendations on - the needs of the Loch Lomond and Trossachs National Park as regards the metadata, metadata standards, and metadata management required for the competent handling of digital materials both now and in the future.
Nicholson, Dennis
core
The case for metadata harvesting [PDF]
, 2004 Metadata harvesting is an increasingly popular model of interaction between the mutually autonomous parties of medium, medium-large federations of digital library services.
ARIIC +10 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Journal of Data and Information Science, 2017 The purpose of the paper is to provide a framework for addressing the disconnect between metadata and data science. Data science cannot progress without metadata research.
Greenberg Jane
doaj +1 more source
Exposing and harvesting metadata using the OAI metadata harvesting protocol: A tutorial [PDF]
, 2001 In this article I outline the ideas behind the Open Archives Initiative metadata harvesting protocol (OAIMH), and attempt to clarify some common misconceptions. I then consider how the OAIMH protocol can be used to expose and harvest metadata.
Warner, Simeon
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Bridging the Gap Between Process and Procedural Provenance for Statistical Data
International Journal of Digital CurationWe show how two models of provenance can work together to answer basic questions about data provenance, such as “What computed variables were affected by values of variable X?”.
Timothy McPhillips +6 more
doaj +1 more source