Results 111 to 120 of about 143,921 (267)
Advanced Science, EarlyView.Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang +12 more
wiley +1 more source
Realization of Semantic Atom Blog
, 2009 Web blog is used as a collaborative platform to publish and share information. The information accumulated in the blog intrinsically contains the knowledge. The knowledge shared by the community of people has intangible value proposition.
Khuba, Sidheshwar A., Patel, Dhiren R.
core
Extending the 5S Framework of Digital Libraries to support Complex Objects, Superimposed Information, and Content-Based Image Retrieval Services [PDF]
, 2010 Advanced services in digital libraries (DLs) have been developed and widely used to address the required capabilities of an assortment of systems as DLs expand into diverse application domains.
Archer, David +8 more
core +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
THE ISSUE OF SEMANTIC MODELING OF THE LEARNING ORGANIZATIONAL MEMORY FOR E-LEARNING [PDF]
The development of open and long-distance learning – within universities but also withingeographically distributed enterprises –has led to the development of researches focusing on modeling onsemantic bases the learning organizational memory of an e ...
Ofelia Ema Aleca, Vasile Florescu
core
The Wiltshire Wills Feasibility Study [PDF]
, 2000 The Wiltshire and Swindon Record Office has nearly ninety thousand wills in its care. These records are neither adequately catalogued nor secured against loss by facsimile microfilm copies.
Gow, Ann, Ross, Seamus
core
Optimal Grazing Exclusion Duration to Enhance Soil Carbon Sequestration in Degraded Grasslands
Advanced Science, EarlyView.Across China, grazing exclusion reaches the national mean soil organic carbon recovery benchmark sooner in high‐MAP regions (> 500 mm), but recovery is much slower where MAP < 300 mm. Scaling this strategy to 70% of China's degraded grasslands would sequester about 1.52 Pg of soil carbon over 10 years—roughly 17% of annual global fossil‐fuel emissions.
Bin Zhang +9 more
wiley +1 more source
A Collaborative Workflow for Digitization of Unique Materials [PDF]
, 2009 This paper examines the experience of one institution, the University of Maryland Libraries, as it made organizational efforts to harness existing workflows and to capture digitization done in the course of responding to patron requests. By examining the
Gueguen, Gretchen, Hanlon, Ann
core +1 more source
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Quality interoperability within digital libraries: the DL.org perspective [PDF]
, 2010 Quality is the most dynamic aspect of DLs, and becomes even more complex with respect to interoperability. This paper formalizes the research motivations and hypotheses on quality interoperability conducted by the Quality Working Group
Clavel, G. +6 more
core +1 more source