Results 51 to 60 of about 60,710 (308)

Quality assurance for digital learning object repositories: issues for the metadata creation process [PDF]

open access: yes, 2004
Metadata enables users to find the resources they require, therefore it is an important component of any digital learning object repository. Much work has already been done within the learning technology community to assure metadata quality, focused on ...
Currier, Sarah   +11 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

ISO 19115 for GeoWeb services orchestration

open access: yesGeoinformatics FCE CTU, 2009
The paper describes theoretical and practical possibilities of ISO 19115 standard in a process of generating dynamic GeoWeb services orchestras. There are several ways how to instantiate orchestras according to current state of services and user needs ...
Jan Růžička
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Evaluating Multilingual Metadata Quality in Crossref

open access: yesJournal of Librarianship and Scholarly Communication
Introduction: Scholarly research spans multiple languages, making multilingual metadata crucial for organizing and accessing knowledge across linguistic boundaries. These multilingual metadata already exist and are propagated throughout the scholarly publishing infrastructure, but the extent to which they are correctly recorded, or how they affect ...
Dennis Donathan II   +4 more
openaire   +2 more sources

The design of an automated workflow for metadata generation

open access: yes, 2010
The important role of digital resources relies on whether metadata is available and has been correctly catalogued and indexed so that the user can discover and use geospatial datasets.
Wachowicz, Monica   +5 more
core   +1 more source

Towards a conceptual framework for user-driven semantic metadata interoperability in digital libraries: A social constructivist approach [PDF]

open access: yes, 2012
Purpose – With the aim of developing a conceptual framework which aims to facilitate semantic metadata interoperability, this paper explores overarching conceptual issues on how traditional library information organization schemes such as Online Public ...
Ross, Penny   +2 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Metadata Extraction and Management in Data Lakes With GEMMS

open access: yesComplex Systems Informatics and Modeling Quarterly, 2016
In addition to volume and velocity, Big data is also characterized by its variety. Variety in structure and semantics requires new integration approaches which can resolve the integration challenges also for large volumes of data.
Christoph Quix, Rihan Hai, Ivan Vatov
doaj   +1 more source

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