Results 111 to 120 of about 43,311 (300)
Advanced Science, EarlyView.This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Advanced Science, EarlyView.Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
IASSIST QuarterlyAs the DDI community continues to grow, an increasing number of repositories are providing their metadata in various DDI formats. However, the current landscape of DDI metadata standards usage is not well understood.
Knut Wenzig, Xiaoyao Han
doaj +1 more source
, 2013 The one-covers-all approach in current metadata standards for scientific data has serious limitations in keeping up with the ever-growing data and being built as part of a metadata infrastructure.
Li, Kai, Qin, Jian
core
Advanced Science, EarlyView.Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang +2 more
wiley +1 more source
Deliverable D3.6.2 (Clusters of agrosystems data in accordance with relevant legal categories) revealed significant differences in licensing practices, access restrictions, data protection considerations and regulatory obligations among FAIRagro’s Research Data Infrastructures (RDIs).
Scheuner, Carmen +2 more
openaire +2 more sources
, 2001 The proliferation of digitized resources accessible via Internet and Intranet knowledge bases, and a pressing need to develop more sophisticated tools for the identification and retrieval of electronic resources, both general purpose and domain-specific ...
Howarth, Lynne C.
core
Bridging the Gap Between Traditional Metadata and the Requirements of an Academic SDI for Interdisciplinary Research [PDF]
, 2012 Metadata has long been understood as a fundamental component of any Spatial Data Infrastructure, providing information relating to discovery, evaluation and use of datasets and describing their quality. Having good metadata about a dataset is fundamental
Winer, Daniel +3 more
core
Advanced Science, EarlyView.Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin +12 more
wiley +1 more source