The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid
Functional bacterial amyloids such as CsgA and FapC have been widely studied to understand the relationship between aggregation and function. The recently solved structure of FapC reveals a Greek‐key motif in which extensive hydrogen bonding and packing interactions formed by residues in conserved imperfect repeats stabilize a β‐solenoid core.
Samuel Peña‐Díaz +12 more
wiley +1 more source
Metagenome microbial communities of bottom sediments of the Kara Sea
Thomasgbif
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Personalised azithromycin+metronidazole (PAZAZ), in combination with standard induction therapy, to achieve a faecal microbiome community structure and metagenome changes associated with sustained remission in paediatric Crohn’s disease (CD): protocol of a pilot study [PDF]
Charlotte M. Verburgt +12 more
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Abstract Alzheimer's disease (AD) is projected to become the highest‐burden neurological disorder globally. Mounting evidence implicates the gut microbiome in AD pathogenesis. This scoping review of gut microbiomes in mild cognitive impairment (MCI) and AD included dietary and probiotic interventions.
Alison Warren +10 more
wiley +1 more source
The Host Coral Bleaching Response Viewed Through the Lens of Multi‐Omics
Coral bleaching is driven by multiple inputs, with heat stress and/or high irradiance being most important. The bleaching response is multifactorial with host animal species/strain and algal symbiont genotypes being critical features. Omics readout of heat stress responses includes gene expression, proteomics, metabolite, and SNP data with transcript ...
Debashish Bhattacharya +4 more
wiley +1 more source
To enable whole‐cell PET valorization, PETCAT is constructed as a two‐strain Escherichia coli system: one engineered to secrete the human saliva metagenomic PET hydrolase optimized for PET degradation at moderate temperatures; and another harboring a synthetic pathway for the conversion of terephthalic acid, a major PET monomer, into catechol—a ...
Rawiporn Amornloetwattana +9 more
wiley +1 more source
Comparative mangrove metagenome reveals global prevalence of heavy metals and antibiotic resistome across different ecosystems [PDF]
Madangchanok Imchen +8 more
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Carnelian uncovers hidden functional patterns across diverse study populations from whole metagenome sequencing reads [PDF]
Sumaiya Nazeen +2 more
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Pea and canola enrich distinct rhizosphere bacterial communities even under intercropping
Abstract Microorganisms have implications for plant health and agricultural production, yet we are just beginning to understand the complexity of plant–microbe interactions in multispecies environments. Studies conducted to date have shown that plants are able to control the makeup of their microbial communities, yet their ability to control these ...
Janice M. Parks +2 more
wiley +1 more source

