Results 241 to 250 of about 173,492 (295)
Bringing Gene Therapy Into Real World Clinical Practice
Haemophilia, EarlyView.ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach +2 more
wiley +1 more source
Diet breadth shapes gut microbiota in the invasive hornet Vespa velutina
Insect Conservation and Diversity, EarlyView.Dietary and microbial profiles of V. velutina larvae are dominated by Apidae and Firmicutes, respectively. DNA metabarcoding of larval meconium and gut samples reveals a significant positive correlation between prey richness and bacterial diversity in the invasive hornet V. velutina. Multiple significant correlations exist between dietary and microbial
Cayetano Herrera +3 more
wiley +1 more source
A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations
International Journal of Cosmetic Science, EarlyView.Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos +3 more
wiley +1 more source
Predictive Biomarkers for Sustained Unresponsiveness Following Oral Immunotherapy
Clinical &Experimental Allergy, EarlyView.
Duan Ni, Ralph Nanan
wiley +1 more source
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Letters in Applied Microbiology, 2008
The total number of prokaryotic cells on earth has been estimated to be approximately 4-6 x 10(30), with the majority of these being uncharacterized. This diversity represents a vast genetic bounty that may be exploited for the discovery of novel genes, entire metabolic pathways and potentially valuable end-products thereof.
R D, Sleator, C, Shortall, C, Hill
+5 more sources
The total number of prokaryotic cells on earth has been estimated to be approximately 4-6 x 10(30), with the majority of these being uncharacterized. This diversity represents a vast genetic bounty that may be exploited for the discovery of novel genes, entire metabolic pathways and potentially valuable end-products thereof.
R D, Sleator, C, Shortall, C, Hill
+5 more sources
2011
Metagenomics has evolved over the last 3 decades from the analysis of single genes and their apparent diversity in an ecosystem to the provision of complex genetic information relating to whole ecosystems. Metagenomics is a vast subject area in terms of methodology, which encompasses a suite of molecular technologies employed to investigate genomic ...
Jack A, Gilbert +5 more
openaire +2 more sources
Metagenomics has evolved over the last 3 decades from the analysis of single genes and their apparent diversity in an ecosystem to the provision of complex genetic information relating to whole ecosystems. Metagenomics is a vast subject area in terms of methodology, which encompasses a suite of molecular technologies employed to investigate genomic ...
Jack A, Gilbert +5 more
openaire +2 more sources
2007
The vast majority of novel DNA sequences deposited in the databases now comes from environmental phage DNA sequences. Methods are presented for the cloning and sequencing of phage DNA that might otherwise be lethal to bacterial host vectors or contain modified DNA bases that prevent standard cloning of such sequences. In addition, methods are presented
Veronica, Casas, Forest, Rohwer
openaire +2 more sources
The vast majority of novel DNA sequences deposited in the databases now comes from environmental phage DNA sequences. Methods are presented for the cloning and sequencing of phage DNA that might otherwise be lethal to bacterial host vectors or contain modified DNA bases that prevent standard cloning of such sequences. In addition, methods are presented
Veronica, Casas, Forest, Rohwer
openaire +2 more sources