Results 231 to 240 of about 133,465 (266)

Calibrating tetranucleotide-frequency distances for metagenomic binning with right-skewed distribution models. [PDF]

Bioinform Adv
Hajjaji O, Al-Soudy AS, Daoud R, Benhida R, Mokhtar MM.   +4 more
europepmc   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Washed Microbiota Transplantation Improves Chronic‐Phase Febrile Infection‐Related Epilepsy Syndrome: The First Case Report With Long‐Term Follow‐Up and Integrated Multi‐Omics Analysis

Microbiota Medicine Research, EarlyView.
ABSTRACT Background Febrile infection‐related epilepsy syndrome (FIRES) is a catastrophic epileptic encephalopathy. Survivors often enter a chronic phase characterized by drug‐resistant epilepsy, cognitive impairment, behavioral and psychiatric symptoms, and long‐term functional disability.
Qianqian Li, Xiao Ding, Sheng Zhang, Faming Zhang   +3 more
wiley   +1 more source

The Prokaryotic Community of Hypersaline Soils from the Odiel Saltmarshes: Culturomics Versus Metagenomics. [PDF]

Life (Basel)
Galisteo C, Straková D, García-Roldán A, de la Haba RR, Sánchez-Porro C, Ventosa A.   +5 more
europepmc   +1 more source

Rapid Metagenomic Detection of <i>Brucella abortus</i> During a Two-Case Bovine Abortion Investigation in Inner Mongolia, China. [PDF]

Vet Sci
Xue T, Zhang B, Wang Z, Ma Y, Shen Q, Ding J, Yang X.   +6 more
europepmc   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Ecological restructuring of the nonbacterial fecal microbiome in obesity across human cohorts. [PDF]

Gut Microbes
Gallardo-Nuell L, Rosell-Díaz M, Garre-Olmo J, Puig J, Ramos R, Pons J, Pérez-Brocal V, Moya A, Mayneris-Perxachs J, Fernández-Real JM.   +9 more
europepmc   +1 more source

Rethinking intensification: Biodiversity‐inclusive management sustains coconut yields

PLANTS, PEOPLE, PLANET, EarlyView.
Coconut palm expansion in West Africa will shape rural livelihoods and ecosystems. Our findings show that intensive practices reduce beneficial soil fungi and increase pathogens, threatening long‐term productivity. Lower‐intensity management that retains ground vegetation can sustain or boost yields while improving soil health.
Benjamin J. Roberts, C. M. ( Tilly) Collins, Konan Engueran Djaha, Hamish Duncalf‐Youngson, Konan Jean Louis, Hala N'klo, Emma Ransome, Doubi Bi Tra Serges, Jahcub Trew, Jake Williams, Vincent Savolainen   +10 more
wiley   +1 more source

Clinical Utility of Metagenomic Next-Generation Sequencing in Adult Patients with Fever of Unknown Origin: A Retrospective Real-World Study. [PDF]

J Clin Med
Guo F, Zhang L, Liu Z, Zhou B, Fan H, Zhang D, Yang Q, Li T, Ge Y.   +8 more
europepmc   +1 more source

Spatial scaling of metagenomic diversity reveals ecological disruption in the gut microbiome of gout patients. [PDF]

Sci Rep
Zhou J, Qiao Y, Chen H, Li L, Su W.
europepmc   +1 more source