Results 211 to 220 of about 145,529 (249)

Pathway-Based Functional Analysis of Metagenomes

Journal of Computational Biology, 2010
Metagenomic data enables the study of microbes and viruses through their DNA as retrieved directly from the environment in which they live. Functional analysis of metagenomes explores the abundance of gene families, pathways, and systems, rather than their taxonomy.
Itai, Sharon, Sivan, Bercovici, Ron Y, Pinter, Tomer, Shlomi   +3 more
openaire   +2 more sources

Metagenomic Analysis of Isotopically Enriched DNA

2010
This detailed protocol describes an approach for combining DNA stable-isotope probing-based enrichment, multiple displacement amplification (MDA), and metagenomics. Together, these three methodologies enable selective access to the genomes of uncultivated organisms that actively grow using isotopically labelled carbon and nitrogen sources.
Yin, Chen, Josh D, Neufeld, Marc G, Dumont, Michael W, Friedrich, J Colin, Murrell   +4 more
openaire   +2 more sources

Metagenomic analysis of stressed coral holobionts

Environmental Microbiology, 2009
Summary The coral holobiont is the community of metazoans, protists and microbes associated with scleractinian corals. Disruptions in these associations have been correlated with coral disease, but little is known about the series of events involved in the shift from mutualism to pathogenesis.
Thurber, Rebecca Vega, Willner-Hall, Dana, Rodriguez-Mueller, Beltran, Desnues, Christelle, Edwards, Robert, Angly, Florent, Dinsdale, Elizabeth, Kelly Wegley, Linda, Rohwer, Forest   +8 more
openaire   +4 more sources

Analysis of Metagenomics Data

2011
Improved sampling of diverse environments and advances in the development and application of next-generation sequencing technologies are accelerating the rate at which new metagenomes are produced. Over the past few years, the major challenge associated with metagenomics has shifted from generating to analyzing sequences.
Elizabeth M. Glass, Folker Meyer
openaire   +1 more source

METHODS OF METAGENOMIC ANALYSIS

МИКРОБИОЛОГИЯ ЖӘНЕ ВИРУСОЛОГИЯ
Metagenomic analysis is a powerful tool for studying the genetic diversity of microorganisms that inhabit different ecological niches. Modern methods of sequencing and bioinformatics analysis allow us to study the taxonomic composition, functional features, and evolutionary patterns of microbial communities without the need for cultivation.
O.N. REVA, L.N. IVANOVA, N.V. ZUBENKO, S.V. SHILOV, T.V. KUZNETSOVA, I.S. KOROTETSKIY   +5 more
openaire   +1 more source

Metagenomic Analysis of Tuberculosis — Current Limitations

New England Journal of Medicine, 2013
To the Editor: Chan and colleagues (July 18 issue)1 describe a mixed-strain infection with two Mycobacterium tuberculosis genotypes in the mummified body of Terezia Hausmann, who died in the late 18th century. This dual infection would not have been detected with the methods of diagnosis in routine use today.
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Metagenomic Analysis of Polar Ecosystems

2014
Polar environments can be among the simplest environments on Earth, making them excellent models to understand ecosystem processes and the responses of microorganisms to environmental perturbations. This vulnerability and the rate of the ongoing change make polar environments a priority in climate change and bioremediation studies.
Etienne Yergeau, Charles W. Greer
openaire   +1 more source

Metagenomic analysis of caseum of tuberculosis foci

Bulletin of Experimental Biology and Medicine
The microbiota of the deep lung regions significantly differs from that of the upper respiratory tract by much lower biomass and dynamic diversity. In our previous studies we found that the biodiversity of the satellite microbiota of tuberculosis foci is sharply reduced in comparison with intact lung tissues.
E A, Orlova, V V, Sinkov, O B, Ogarkov, A E, Suzdalnitsky, I G, Kondratov, S N, Zhdanova, L V, Rychkova, L I, Kolesnikova   +7 more
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Analysis Methods for Shotgun Metagenomics

2018
The development of whole metagenome shotgun sequencing (WGS) has enabled the precise characterization of taxonomic diversity and functional capabilities of microbial communities in situ while obviating organism isolation and cultivation procedures. WGS created with second- and third-generation sequencing technologies will generate millions of reads and
Stephen Woloszynek, Zhengqiao Zhao, Gregory Ditzler, Jacob R. Price, Erin R. Reichenberger, Yemin Lan, Jian Chen, Joshua Earl, Saeed Keshani Langroodi, Garth Ehrlich, Gail Rosen   +10 more
openaire   +1 more source

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly