Results 211 to 220 of about 72,279 (314)

The Gut Microbiome Obesity Index: A New Analytical Tool in the Metagenomics Workflow for the Evaluation of Gut Dysbiosis in Obese Humans. [PDF]

open access: yesNutrients
Kulecka M   +9 more
europepmc   +1 more source

Structure Modeling Protocols for Protein Multimer and RNA in CASP16 With Enhanced MSAs, Model Ranking, and Deep Learning

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the methods and results of our protein complex and RNA structure predictions at CASP16. Our approach integrated multiple state‐of‐the‐art deep learning models with a consensus‐based scoring method. To enhance the depth of multiple sequence alignments (MSAs), we employed a large metagenomic sequence database.
Yuki Kagaya   +10 more
wiley   +1 more source

A systematic benchmark of integrative strategies for microbiome-metabolome data. [PDF]

open access: yesCommun Biol
Mangnier L   +7 more
europepmc   +1 more source

Highlights of Model Quality Assessment in CASP16

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Model quality assessment (MQA) remains a critical component of structural bioinformatics for both structure predictors and experimentalists seeking to use predictions for downstream applications. In CASP16, the Evaluation of Model Accuracy (EMA) category featured both global and local quality estimation for multimeric assemblies (QMODE1 and ...
Alisia Fadini   +23 more
wiley   +1 more source

Faecalibacterium Diversity in the Gut Microbiome of Crohn's Disease Patients

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Faecalibacterium has recently garnered attention for its potential health implications. To better understand its role, we developed and assessed real‐time PCR assays for detecting and quantifying various Faecalibacterium species in human stool samples from both healthy individuals and Crohn's disease patients, either in flare or remission. The
Paul Mclellan   +16 more
wiley   +1 more source

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch   +1 more
wiley   +1 more source

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