From metagenomics to the metagenome: Conceptual change and the rhetoric of translational genomic research [PDF]
, 2009 As the international genomic research community moves from the tool-making efforts of the Human Genome Project into biomedical applications of those tools, new metaphors are being suggested as useful to understanding how our genes work – and for ...
Huss, John Edward, Juengst, Eric Thomas
core +1 more source
A more complete picture: Capturing single nucleotide variant diversity in extended-spectrum beta-lactamase producing Escherichia coli using post-enrichment metagenomics [PDF]
Gallichan S +10 more
europepmc +2 more sources
Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]
, 2019 Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda +7 more
core +1 more source
Bracken: estimating species abundance in metagenomics data
bioRxiv, 2016 We describe a new, highly accurate statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. Bracken (Bayesian Reestimation of Abundance after Classification with KrakEN) uses the taxonomy labels assigned by ...
Jennifer Lu +3 more
semanticscholar +1 more source
Analysis and Interpretation of metagenomics data: an approach
Biological Procedures Online, 2022 Advances in next-generation sequencing technologies have accelerated the momentum of metagenomic studies, which is increasing yearly. The metagenomics field is one of the versatile applications in microbiology, where any interaction in the environment ...
Gauri S. Navgire +7 more
semanticscholar +1 more source
Genome binning of viral entities from bulk metagenomics data
Nature Communications, 2021 Despite the accelerating number of uncultivated virus sequences discovered in metagenomics and their apparent importance for health and disease, the human gut virome and its interactions with bacteria in the gastrointestinal tract are not well understood.
Joachim Johansen +10 more
semanticscholar +1 more source
DNA structure at the plasmid origin-of-transfer indicates its potential transfer range
Scientific Reports, 2018 Horizontal gene transfer via plasmid conjugation enables antimicrobial resistance (AMR) to spread among bacteria and is a major health concern. The range of potential transfer hosts of a particular conjugative plasmid is characterised by its mobility ...
Jan Zrimec, Aleš Lapanje
doaj +1 more source
BMC Genomics, 2023 Background While genome-resolved metagenomics has revolutionized our understanding of microbial and genetic diversity in environmental samples, assemblies of short-reads often result in incomplete and/or highly fragmented metagenome-assembled genomes ...
Sophie A. Simon +5 more
doaj +1 more source
Combination of Whole Genome Sequencing and Metagenomics for Microbiological Diagnostics
International Journal of Molecular Sciences, 2022 Whole genome sequencing (WGS) provides the highest resolution for genome-based species identification and can provide insight into the antimicrobial resistance and virulence potential of a single microbiological isolate during the diagnostic process.
Srinithi Purushothaman +2 more
semanticscholar +1 more source
Giant virus diversity and host interactions through global metagenomics
Nature, 2020 Our current knowledge about nucleocytoplasmic large DNA viruses (NCLDVs) is largely derived from viral isolates that are co-cultivated with protists and algae.
Frederik Schulz +10 more
semanticscholar +1 more source