Metagenomics Approaches for the Detection and Surveillance of Emerging and Recurrent Plant Pathogens
Globalization has a dramatic effect on the trade and movement of seeds, fruits and vegetables, with a corresponding increase in economic losses caused by the introduction of transboundary plant pathogens.
E. Piombo+5 more
semanticscholar +1 more source
Proteomics as the final step in the functional metagenomics study of antimicrobial resistance [PDF]
peer-reviewedThe majority of clinically applied antimicrobial agents are derived from natural products generated by soil microorganisms and therefore resistance is likely to be ubiquitous in such environments.
Cotter, Paul D.+4 more
core +1 more source
Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage
Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining representative data on AMR for healthy human populations is difficult. Here, we use metagenomic analysis of untreated sewage to characterize the bacterial resistome
R. Hendriksen+32 more
semanticscholar +1 more source
From metagenomics to the metagenome: Conceptual change and the rhetoric of translational genomic research [PDF]
As the international genomic research community moves from the tool-making efforts of the Human Genome Project into biomedical applications of those tools, new metaphors are being suggested as useful to understanding how our genes work – and for ...
Huss, John Edward, Juengst, Eric Thomas
core +1 more source
DNA structure at the plasmid origin-of-transfer indicates its potential transfer range
Horizontal gene transfer via plasmid conjugation enables antimicrobial resistance (AMR) to spread among bacteria and is a major health concern. The range of potential transfer hosts of a particular conjugative plasmid is characterised by its mobility ...
Jan Zrimec, Aleš Lapanje
doaj +1 more source
Background While genome-resolved metagenomics has revolutionized our understanding of microbial and genetic diversity in environmental samples, assemblies of short-reads often result in incomplete and/or highly fragmented metagenome-assembled genomes ...
Sophie A. Simon+5 more
doaj +1 more source
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
“Normal” for the gut microbiota For the benefit of future clinical studies, it is critical to establish what constitutes a “normal” gut microbiome, if it exists at all. Through fecal samples and questionnaires, Falony et al.
A. Zhernakova+30 more
semanticscholar +1 more source
Giant virus diversity and host interactions through global metagenomics
Our current knowledge about nucleocytoplasmic large DNA viruses (NCLDVs) is largely derived from viral isolates that are co-cultivated with protists and algae.
Frederik Schulz+10 more
semanticscholar +1 more source
Integrating Viral Metagenomics into an Ecological Framework.
Viral metagenomics has expanded our knowledge of the ecology of uncultured viruses, within both environmental (e.g., terrestrial and aquatic) and host-associated (e.g., plants and animals, including humans) contexts. Here, we emphasize the implementation
P. Sommers+3 more
semanticscholar +1 more source
Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda+7 more
core +1 more source