Results 31 to 40 of about 72,279 (314)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Metagenomic Analysis of Silage [PDF]

Journal of Visualized Experiments, 2017
Metagenomics is defined as the direct analysis of deoxyribonucleic acid (DNA) purified from environmental samples and enables taxonomic identification of the microbial communities present within them. Two main metagenomic approaches exist; sequencing the 16S rRNA gene coding region, which exhibits sufficient variation between taxa for identification ...
Tennant, RK, Sambles, CM, Diffey, GE, Moore, KA, Love, J   +4 more
openaire   +4 more sources

A database of animal metagenomes

Scientific Data, 2022
AbstractWith the rapid development of high-throughput sequencing technology, the amount of metagenomic data (including both 16S and whole-genome sequencing data) in public repositories is increasing exponentially. However, owing to the large and decentralized nature of the data, it is still difficult for users to mine, compare, and analyze the data ...
Hu, Ruirui, Yao, Rui, Li, Lei, Xu, Yueren, Lei, Bingbing, Tang, Guohao, Liang, Haowei, Lei, Yunjiao, Li, Cunyuan, Li, Xiaoyue, Liu, Kaiping, Wang, Limin, Zhang, Yunfeng, Wang, Yue, Cui, Yuying, Dai, Jihong, Ni, Wei, Zhou, Ping, Yu, Baohua, Hu, Shengwei   +19 more
openaire   +3 more sources

An overlooked phenomenon: complex interactions of potential error sources on the quality of bacterial de novo genome assemblies

BMC Genomics
Background Parameters adversely affecting the contiguity and accuracy of the assemblies from Illumina next-generation sequencing (NGS) are well described.
Zoltán Rádai, Alex Váradi, Péter Takács, Nikoletta Andrea Nagy, Nicholas Schmitt, Eszter Prépost, Gábor Kardos, Levente Laczkó   +7 more
doaj   +1 more source

Maximal viral information recovery from sequence data using VirMAP

Nature Communications, 2018
Viral taxonomic characterization from metagenomic data suffers from high background noise and signal crosstalk. Here, the authors develop VirMAP, a novel pipeline for analyses of metagenomic data that classifies viral reconstructions independent of ...
Nadim J Ajami, Matthew C. Wong, Matthew C. Ross, Richard E. Lloyd, Joseph F. Petrosino   +4 more
doaj   +1 more source

IL17eScan: A Tool for the Identification of Peptides Inducing IL-17 Response

Frontiers in Immunology, 2017
IL-17 cytokines are pro-inflammatory cytokines and are crucial in host defense against various microbes. Induction of these cytokines by microbial antigens has been investigated in the case of ischemic brain injury, gingivitis, candidiasis, autoimmune ...
Sudheer Gupta, Parul Mittal, Midhun K. Madhu, Vineet K. Sharma   +3 more
doaj   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

Metagenome of a polluted river reveals a reservoir of metabolic and antibiotic resistance genes

Environmental Microbiome, 2019
Background Yamuna, a major tributary of Ganga, which flows through the national capital region of Delhi, is among the major polluted rivers in India. The accumulation of various effluents, toxic chemicals, heavy metals, and increased organic load in the ...
Parul Mittal, Vishnu Prasoodanan PK, Darshan B. Dhakan, Sanjiv Kumar, Vineet K. Sharma   +4 more
doaj   +1 more source

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

The gut mycobiome of the Human Microbiome Project healthy cohort

Microbiome, 2017
Background Most studies describing the human gut microbiome in healthy and diseased states have emphasized the bacterial component, but the fungal microbiome (i.e., the mycobiome) is beginning to gain recognition as a fundamental part of our microbiome ...
Andrea K. Nash, Thomas A. Auchtung, Matthew C. Wong, Daniel P. Smith, Jonathan R. Gesell, Matthew C. Ross, Christopher J. Stewart, Ginger A. Metcalf, Donna M. Muzny, Richard A. Gibbs, Nadim J. Ajami, Joseph F. Petrosino   +11 more
doaj   +1 more source