Results 31 to 40 of about 173,789 (325)

Genome binning of viral entities from bulk metagenomics data

open access: yesNature Communications, 2021
Despite the accelerating number of uncultivated virus sequences discovered in metagenomics and their apparent importance for health and disease, the human gut virome and its interactions with bacteria in the gastrointestinal tract are not well understood.
Joachim Johansen   +10 more
semanticscholar   +1 more source

CoverM: read alignment statistics for metagenomics [PDF]

open access: yesBioinformatics
Summary Genome-centric analysis of metagenomic samples is a powerful method for understanding the function of microbial communities. Calculating read coverage is a central part of analysis, enabling differential coverage binning for recovery of genomes ...
Samuel T. N. Aroney   +5 more
semanticscholar   +1 more source

Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]

open access: yes, 2019
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda   +7 more
core   +1 more source

DNA structure at the plasmid origin-of-transfer indicates its potential transfer range

open access: yesScientific Reports, 2018
Horizontal gene transfer via plasmid conjugation enables antimicrobial resistance (AMR) to spread among bacteria and is a major health concern. The range of potential transfer hosts of a particular conjugative plasmid is characterised by its mobility ...
Jan Zrimec, Aleš Lapanje
doaj   +1 more source

Dancing the Nanopore limbo – Nanopore metagenomics from small DNA quantities for bacterial genome reconstruction

open access: yesBMC Genomics, 2023
Background While genome-resolved metagenomics has revolutionized our understanding of microbial and genetic diversity in environmental samples, assemblies of short-reads often result in incomplete and/or highly fragmented metagenome-assembled genomes ...
Sophie A. Simon   +5 more
doaj   +1 more source

A Vavilovian approach to discovering crop-associated microbes with potential to enhance plant immunity [PDF]

open access: yes, 2014
Through active associations with a diverse community of largely non-pathogenic microbes, a plant may be thought of as possessing an “extended genotype,” an interactive cross-organismal genome with potential, exploitable implications for plant immunity ...
Broders, Kirk   +2 more
core   +3 more sources

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

open access: yesScience, 2016
“Normal” for the gut microbiota For the benefit of future clinical studies, it is critical to establish what constitutes a “normal” gut microbiome, if it exists at all. Through fecal samples and questionnaires, Falony et al.
A. Zhernakova   +30 more
semanticscholar   +1 more source

Spaced seeds improve k-mer-based metagenomic classification [PDF]

open access: yes, 2015
Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the analysis of k ...
Brinda, Karel   +2 more
core   +2 more sources

Benchmark of 16S rRNA gene amplicon sequencing using Japanese gut microbiome data from the V1–V2 and V3–V4 primer sets

open access: yesBMC Genomics, 2021
Background 16S rRNA gene amplicon sequencing (16S analysis) is widely used to analyze microbiota with next-generation sequencing technologies. Here, we compared fecal 16S analysis data from 192 Japanese volunteers using the modified V1–V2 (V12) and the ...
Shoichiro Kameoka   +9 more
doaj   +1 more source

Genomic Characterization of a Prophage, Smhb1, That Infects Salinivibrio kushneri BNH Isolated from a Namib Desert Saline Spring

open access: yesMicroorganisms, 2021
Recent years have seen the classification and reclassification of many viruses related to the model enterobacterial phage P2. Here, we report the identification of a prophage (Smhb1) that infects Salinivibrio kushneri BNH isolated from a Namib Desert ...
Israel Olonade   +2 more
doaj   +1 more source

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