Results 61 to 70 of about 82,780 (305)

Translational metagenomics [PDF]

Journal of Translational Medicine, 2021
Selvasankar Murugesan, Souhaila Al Khodor   +1 more
openaire   +3 more sources

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

A study of innate immune kinetics reveals a role for a chloride transporter in a virulent Francisella tularensis type B strain

MicrobiologyOpen, 2021
Tularemia is a zoonotic disease of global proportions. Francisella tularensis subspecies tularensis (type A) and holarctica (type B) cause disease in healthy humans, with type A infections resulting in higher mortality.
Lisa M. Matz, Joseph F. Petrosino
doaj   +1 more source

Tales from the crypt and coral reef: the successes and challenges of identifying new herpesviruses using metagenomics. [PDF]

, 2015
Herpesviruses are ubiquitous double-stranded DNA viruses infecting many animals, with the capacity to cause disease in both immunocompetent and immunocompromised hosts.
Charlotte J. Houldcroft, Houldcroft, CJ, Breuer, J, Judith Breuer   +3 more
core   +2 more sources

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

Gut Microbiota in Type 2 Diabetes and Metabolic Disorders: Sources of Heterogeneity and Ways to Resolve Contradictions in Research

Diabetology
Metabolic diseases, including obesity and type 2 diabetes mellitus, represent a major global health burden and are closely linked to the composition and function of the gut microbiota.
Ekaterina Nesterova, Maria Gladkikh, Inna Burakova, Olga Korneeva, Polina Morozova, Mikhail Syromyatnikov   +5 more
doaj   +1 more source

The Gene Catalog and Comparative Analysis of Gut Microbiome of Big Cats Provide New Insights on Panthera Species

Frontiers in Microbiology, 2020
Majority of metagenomic studies in the last decade have focused on revealing the gut microbiomes of humans, rodents, and ruminants; however, the gut microbiome and genic information (gene catalog) of large felids such as Panthera species are largely ...
Parul Mittal, Rituja Saxena, Atul Gupta, Shruti Mahajan, Vineet K. Sharma   +4 more
doaj   +1 more source

Longitudinal study of the scalp microbiome suggests coconut oil to enrich healthy scalp commensals

Scientific Reports, 2021
Dandruff is a recurrent chronic scalp disorder, affecting majority of the population worldwide. Recently a metagenomic study of the Indian scalp microbiome described an imperative role of bacterial commensals in providing essential vitamins and amino ...
Rituja Saxena, Parul Mittal, Cecile Clavaud, Darshan B. Dhakan, Nita Roy, Lionel Breton, Namita Misra, Vineet K. Sharma   +7 more
doaj   +1 more source

Metagenomic Association Uncovers Host Genotype‐Structured Rhizobacterial Networks and Novel Taxa That Enhance Soybean Salt Tolerance

Advanced Science, EarlyView.
An STI‐guided metagenomic association framework links soybean salt‐tolerance phenotypes with rhizosphere microbiome composition and network organization in natural saline soils. The approach identifies candidate beneficial taxa, including Thalassospira xiamenensis, and provides an efficient strategy for mining stress‐protective microbes from native ...
Yu Luo, Feng‐Li Kang, Qi‐Min Li, Wei‐Cai Yang   +3 more
wiley   +1 more source

Diversity of dsDNA Viruses in a South African Hot Spring Assessed by Metagenomics and Microscopy

Viruses, 2017
The current view of virus diversity in terrestrial hot springs is limited to a few sampling sites. To expand our current understanding of hot spring viral community diversity, this study aimed to investigate the first African hot spring (Brandvlei hot ...
Olivier Zablocki, Leonardo Joaquim van Zyl, Bronwyn Kirby, Marla Trindade   +3 more
doaj   +1 more source