Results 41 to 50 of about 2,343,514 (318)

Assessment of metals contamination and ecological risk in ait Ammar abandoned iron mine soil, Morocco

open access: yesEkológia (Bratislava), 2016
The present study is an attempt to assess the pollution intensity and corresponding ecological risk of phosphorus and metals including Cd, Cr, Cu, Zn, Pb and Fe using various indices like geo-accumulation index, enrichment factor, pollution and ...
Nouri Mohamed, Haddioui Abd El Majid
doaj   +1 more source

Mapping differential elemental accumulation in fish tissues: Importance of fish tissue sampling standardization [PDF]

open access: yesArchives of Biological Sciences, 2016
The concentrations of As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se and Zn in the muscle, gills, liver and intestine of the wels catfish (Silurus glanis) from the Danube River were analyzed by inductively coupled plasma mass spectrometry (ICP-MS ...
Jovičić Katarina   +8 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Convertible metal-backed glenoid in total shoulder arthroplasty: a single-centre case series with minimum 15 years’ follow-up

open access: yesBone & Joint Open
Aims: The aim of this study was to report long-term clinical outcomes of a modern convertible metal-backed glenoid (MBG) in total shoulder arthroplasty (TSA). Methods: After a minimum of 15 years, a previously studied cohort of 35 patients who received
Riccardo Ranieri   +5 more
doaj   +1 more source

Antibiotic and Metal Resistance in Escherichia coli Isolated from Pig Slaughterhouses in the United Kingdom

open access: yesAntibiotics, 2020
Antimicrobial resistance is currently an important concern, but there are few data on the co-presence of metal and antibiotic resistance in potentially pathogenic Escherichia coli entering the food chain from pork, which may threaten human health.
Hongyan Yang   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Investigation of advanced strain-path dependent material models for sheet metal forming simulations [PDF]

open access: yes, 2006
Sheet metal forming processes often involve complex loading sequences. To improve the prediction of some undesirable phenomena, such as springback, physical behavior models should be considered.
BALAN, Tudor   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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