Results 51 to 60 of about 2,784,732 (310)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Recent Advancements in Post Processing of Additively Manufactured Metals Using Laser Polishing

open access: yesJournal of Manufacturing and Materials Processing, 2023
The poor surface roughness associated with additively manufactured parts can influence the surface integrity and geometric tolerances of produced components.
Majed Ali   +3 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Alumina-Sic Partikül Destekli T/M Al-Matriksli Kompozitlerin Üretilmesi Ve Mekanik Özelliklerinin İncelenmesi [PDF]

open access: yes, 2007
06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Ekerer, Feyzullah Alpaslan   +2 more
core  

Trace element composition of troilite, iron and iron-nickel metall from meteorite Chelyabinsk

open access: yesЛитосфера, 2015
We studied the contents of trace elements in troilite, iron and in iron-nickel metal from meteorite Chelyabinsk by means of LA-ICP-MS. The features of the distribution of siderophile and chalcophile elements in sulfide and metallic phase in gray and ...
S. Yu. Stepanov, S. V. Berzin
doaj   +2 more sources

Beyond the Toolpath: Site-Specific Melt Pool Size Control Enables Printing of Extra-Toolpath Geometry in Laser Wire-Based Directed Energy Deposition

open access: yesApplied Sciences, 2019
A variety of techniques have been utilized in metal additive manufacturing (AM) for melt pool size management, including modeling and feed-forward approaches. In a few cases, closed-loop control has been demonstrated.
Brian T. Gibson   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Fabrication of crystals from single metal atoms [PDF]

open access: yes, 2014
Metal nanocrystals offer new concepts for the design of nanodevices with a range of potential applications. Currently the formation of metal nanocrystals cannot be controlled at the level of individual atoms. Here we describe a new general method for the
Smith, C.J.   +34 more
core   +1 more source

Ювелирное искусство Екатеринбурга конца XX – начала XXI века

open access: yesИскусство Евразии, 2019
В статье кратко рассмотрены три основных этапа развития ювелирного искусства Екатеринбурга конца XX начала XXI века. Приведены общие временные истилистические особенности каждого периода.
Глазырин, Кирилл Николаевич
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

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