Results 61 to 70 of about 2,754,118 (311)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Sur la piste du mort habillé

open access: yesLes Nouvelles de l’Archéologie, 2013
Following the death of an individual, a human group gets busy to make mourning of it since taken care of death until the lapse of memory. This text deals with one of the first times of this funerary operational chain, that of the preparation and the ...
Jean-Gabriel Pariat, Florence Dussère
doaj   +1 more source

Ark Kaynak Parametrelerinin Sanal Kaynak Simülatörüne Entegrasyonu [PDF]

open access: yes, 2012
06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Yardımcı Doçent Doktor Uğur Soy   +2 more
core  

Metal-metal bonding in poly-metallic systems [PDF]

open access: yes, 2019
This thesis focuses on the nature of metal-metal bonding in poly-metallic systems. The electronic structures of examples of this class are studied using both density functional theory (DFT), time-dependent density functional theory (TD-DFT), periodic ...
AL-Nafee, Mohammed
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Parkinson’s disease and occupational exposures: a systematic literature review and meta-analyses

open access: yesScandinavian Journal of Work, Environment & Health, 2017
OBJECTIVES: We conducted a systematic literature review to identify studies fulfilling good scientific epidemiological standards for use in meta-analyses of relevant risk factors for Parkinson’s disease.
Lars-Gunnar Gunnarsson, Lennart Bodin
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

VALORISATION OF ADORNMENTS IN THE PROFESSIONAL TRAINING OF STUDENTS [PDF]

open access: yesStudiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2022
The present paper is intended for the students of the Decorative Art speciality, the discipline - Artistic Processing of Metal and Jewelry. In order to make an ornament, it is necessary to know the materials, tools and the execution stages, which will ...
MATCAN-LISENCO, INGA
doaj  

Gemi Saclarının Kaynak Bağlantılarında Kaynak Parametrelerinin Dikiş Geometrisine Etkisinin İncelenmesi [PDF]

open access: yes, 2009
06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Sakarya Üniversitesi, Fen Bilimleri Enstitüsü, Metal Eğitimi Anabilim Dalı, Metal Eğitimi   +2 more
core  

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