Results 61 to 70 of about 4,957,448 (283)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Copper in Galician ria sediments: natural levels and harbour contamination

open access: yesScientia Marina, 2013
Copper distribution, natural background and contamination levels in sediments of the Galician rias were assessed from 389 surface sediment samples and five sediment cores.
Ana García   +2 more
doaj   +1 more source

Early stages of phase selection in MOF formation observed in molecular Monte Carlo simulations [PDF]

open access: yes, 2019
Metal-organic frameworks (MOF) comprising metal nodes bridged by organic linkers show great promise because of their guest-specific gas sorption, separation, drug-delivery, and catalytic properties.
Cessford, Naomi F.   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A local metallic state in globally insulating $La_{1.24}Sr_{1.76}Mn_2O_7$ well above the metal-insulator transition

open access: yes, 2006
Angle-resolved photoemission spectroscopy was used to investigate the evolution of the electronic structure across the metal-insulator transition in bi-layer manganite $La_{1.24}Sr_{1.76}Mn_2O_7$.
Chuang, Y. -D.   +6 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Trace element composition of troilite, iron and iron-nickel metall from meteorite Chelyabinsk

open access: yesЛитосфера, 2015
We studied the contents of trace elements in troilite, iron and in iron-nickel metal from meteorite Chelyabinsk by means of LA-ICP-MS. The features of the distribution of siderophile and chalcophile elements in sulfide and metallic phase in gray and ...
S. Yu. Stepanov, S. V. Berzin
doaj   +2 more sources

Beyond the Toolpath: Site-Specific Melt Pool Size Control Enables Printing of Extra-Toolpath Geometry in Laser Wire-Based Directed Energy Deposition

open access: yesApplied Sciences, 2019
A variety of techniques have been utilized in metal additive manufacturing (AM) for melt pool size management, including modeling and feed-forward approaches. In a few cases, closed-loop control has been demonstrated.
Brian T. Gibson   +3 more
doaj   +1 more source

Metal–Metal Bonding

open access: yes, 2013
This chapter deals with the electronic structure of metal-metal bonds in molecular systems, a diverse topic that now spans almost the entire periodic table. The field is most often associated with strong multiple bonds such as the iconic quadruple bond in [Re2Cl8]2-, and the recently discovered ultra-short Cr-Cr quintuple bonds provide a remarkable ...
openaire   +2 more sources

Metal—Metal Compounds [PDF]

open access: yesNature, 1967
Intermetallic Compounds Edited by J. H. Westbrook. (Wiley Series on the Science and Technology of Materials.) Pp. xvii + 663. (New York and London: John Wiley and Sons, 1967.) 235s.
openaire   +1 more source

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