Results 71 to 80 of about 317,401 (312)
Metals, 2022 The influences of ultrasonic vibration during cold metal transfer welding process on the microstructure, element distribution and pitting resistance of AISI 430 ferritic stainless steel joints with ER 308L as filler metal were investigated.
Naiqiang Xu +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Revista de Metalurgia, 2003 El efecto del metal de soldadura sobre la constricción fuera-del-plano en probetas C(T) bimetálicas fue estudiado utilizando la Ecuación del Formato Común (EEC) y su factor de constricción asociado, Ω*, en función del cociente espesor de probeta a ...
J. R. Donoso, A. Ortiz, F. Labbé
doaj +1 more source
Statistical modelling of the narrow gap gas metal arc welding process [PDF]
, 1990 The J-laying technique for the construction of offshore pipelines requires a fast welding process that can produce sound welds in the horizontal-vertical position.
Modenesi, P. J.
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Metales y aleaciones en odontología
Revista Facultad de Odontología Universidad de Antioquia, 2004 Knowledge of the various dental materials used in Prosthodontics is a paramount necessity for professionals in dentistry. Several metals are routinely used in dentistry for a variety of applications, including the fabrication of dentures, temporary and ...
Olga Lucía Giraldo-R.
doaj
Geodynamic controls on clastic-dominated base metal deposits [PDF]
Solid EarthTo meet the growing global demand for metal resources, new ore deposit discoveries are required. However, finding new high-grade deposits, particularly those not exposed at the Earth's surface, is very challenging. Therefore, understanding the geodynamic
A. C. Glerum +8 more
doaj +1 more source
Materials Research Express, 2020 In this study, dissimilar butt joints were formed between as-rolled Inconel 718 and SUS 316 using cold metal transfer (CMT) with ERNiFeCr-2 filler metal at a welding speed of 5 mm s ^−1 and three different welding currents (130, 160 and 190 A).
YunLong Tang +5 more
doaj +1 more source