Results 91 to 100 of about 317,401 (312)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Geology, fluid inclusions, mineral and (S-O) isotope chemistry of the Badran orogenic Au deposit, Yana-Kolyma belt, eastern Siberia: implications for ore genesis

Frontiers in Earth Science
The Badran orogenic gold deposit is located in the Yana-Kolyma belt, Eastern Siberia; it has proven reserves of ∼9.3 t of gold and an average grade of 7.8 ppm. The total gold production at the Badran deposit since 1984 amounts to ∼34 t.
Valery Fridovsky, Sergey Kryazhev, Sergey Kryazhev, Lena Polufuntikova, Maxim Kudrin, Galina Anisimova   +5 more
doaj   +1 more source

Photochemical reactions of VIB and VIIB group metal carbonyl complexes with a chiral Schiff base

, 2007
The hitherto unknown complexes, [M(CO)(4)(eta(2)-H2L)], [M = Cr; 1, Mo; 2, W; 3]; fac-[Re(CO)(3)Br(eta(2)-H2L)], 4 and [(eta(5)-C5H5)Mn(CO)Br(eta(2)-H2L)], 5 have been synthesized by the photochemical reactions of VIB and VIIB metal carbonyls [M(CO)(6)] [
Temel, Hamdi, Subasi, ELİF
core   +1 more source

Base-Promoted Synthesis of Vinyl Sulfides from Sulfonium Triflates

, 2022
A new protocol has been developed for vinyl sulfide synthesis promoted by an alkoxy base under metal-free conditions. In this reaction, aryl and alkenyl sulfonium triflates with diverse functionalities are converted into vinyl sulfides with excellent ...
Qingzheng Zhang (5515520), Feng Chen (25347), Pan Gao (380188)   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Nanoparticles based on essential metals and their phytotoxicity

Journal of Nanobiotechnology, 2017
Nanomaterials in agriculture are becoming popular due to the impressive advantages of these particles. However, their bioavailability and toxicity are key features for their massive employment. Herein, we comprehensively summarize the latest findings on the phytotoxicity of nanomaterial products based on essential metals used in plant protection.
Branislav Ruttkay-Nedecky, Olga Krystofova, Lukas Nejdl, Vojtech Adam   +3 more
openaire   +4 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Multiaxial Cycle Deformation and Low-Cycle Fatigue Behavior of Mild Carbon Steel and Related Welded-Metal Specimen

Advances in Materials Science and Engineering, 2017
The low-cycle fatigue experiments of mild carbon Q235B steel and its related welded-metal specimens are performed under uniaxial, in-phase, and 90° out-of-phase loading conditions.
Weilian Qu, Ernian Zhao, Qiang Zhou
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source