Results 81 to 90 of about 317,401 (312)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Metal complexes as DNA intercalators [PDF]
, 2011 DNA has a strong affinity for many heterocyclic aromatic dyes, such as acridine and its derivatives. Lerman in 1961 first proposed intercalation as the source of this affinity, and this mode of DNA binding has since attracted considerable research ...
Peter J. Sadler +3 more
core +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
A designed metal-organic framework based on a metal-organic polyhedron [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2008 A C(3) symmetric ligand with three 1,3-benzenedicarboxylate units has been used to construct a metal-organic framework with a (3,24)-connected network topology, where the nanometre-sized metal-organic cuboctahedra (MOCs) have been incorporated solely into a cubic close packing (CCP) arrangement, which led to superoctahedral and supertetrahedral ...
Zou, Yang +3 more
openaire +3 more sources
Advances in Materials Science and Engineering, 2015 Cyclic stress response and fracture behaviors of Alloy 617 base metal (BM) and Alloy 617 weld joints (WJ) are investigated under strain controlled low cycle fatigue (LCF) loading.
Seon Jin Kim +3 more
doaj +1 more source
Design of complete denture reinforced with metal base [PDF]
Stomatološki glasnik Srbije, 2013 Introduction. Complete denture reinforced with metal bases is fabricated in cases of fracture risk as well as in selected patients with neuromuscular disorders.
Poštić Srđan D.
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Influence of Exposure to Environment on Degradation of a Friction Stir Welded Aluminum Alloy
Metals, 2020 We carried out a comparative study on both the stress corrosion response and corrosion damage characteristics of aluminum alloy 2219, both the base material and a friction stir welding (FSW) counterpart upon exposure to exfoliation corrosion (EXCO ...
Shengli Lv +3 more
doaj +1 more source
Heavy metal contamination in some soils of the McMurdo Sound region, Antarctica
, 1995 Soil samples from eight sites at Marble Point and Pram Point, McMurdo Sound region, contaminated by human activities were examined for heavy metal content, using sequential extraction methods.
Campbell, Iain B. +4 more
core +1 more source
, 2022 Herein, the influence of group 1 and 2 metal cations on base-catalyzed dehydrogenative coupling of formate to form oxalate is reported. Treatment of sodium formate with a various types of bases (group 1 and 2 metal carbonates or metal hydroxides ...
Jun-ichiro, Hayashi +3 more
core +1 more source