Results 61 to 70 of about 482,751 (315)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Boletín de la Sociedad Española de Cerámica y Vidrio, 2012 Ferro Spain SA has tackled the practical viability of tile surfaces decoration by means of applying layers of reduced thickness by means of the use of digital injection technology by inkjet and, specifically, relating to effects and superficial finishes ...
Spain S.A., Ferro
doaj
NanomaterialsThis study delves into the distinctive selective property exhibited by a non-conjugated cholesterol-based polymer, poly(CEM11-b-EHA7), in sorting semiconducting single-walled carbon nanotubes (s-SWCNTs) within isooctane.
Ahmad Al Shboul +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Nanometer Scale Atomic Structure of Zirconium Based Bulk Metallic Glass [PDF]
, 2011 We have studied the nanometer scale structure of bulk metallic glass (BMG) using fluctuation electron microscopy (FEM). The nanometer scale medium range order (MRO) in BMG is of significant interest because of its possible relationship to the properties,
Hwang, Jinwoo
core +1 more source
Metallic glass nanofilms [PDF]
, 2011 In this paper, we report for the first time the spontaneous formation of Zr-based metallic glass nanofilms by developed dynamic forced-shear-rupture technique of hat-shaped specimens.
段桂花, 蒋敏强, 戴兰宏
core +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Entropy of Conduction Electrons from Transport Experiments
Entropy, 2020 The entropy of conduction electrons was evaluated utilizing the thermodynamic definition of the Seebeck coefficient as a tool. This analysis was applied to two different kinds of scientific questions that can—if at all—be only partially ...
Nicolás Pérez +7 more
doaj +1 more source
Journal of Physics: Condensed Matter, 2018 Abstract Hydrogen is the simplest and most abundant element in the Universe. There are two pathways for creating metallic hydrogen under high pressures. Over 80 years ago Wigner and Huntington predicted that if solid molecular hydrogen was sufficiently compressed in the T =
Ranga Dias, Isaac Silvera
openaire +2 more sources
Student perspectives on Mi'gmaq language-learning through multi-modal teaching: A community-linguistics partnership [PDF]
, 2013 This paper aims to share the experiences of heritage Mi’gmaq language learners who engaged in a summer Mi'gmaq-as-a-second-language class. Also participating in the class were linguists collaborating with the teachers to document and expand the multi ...
Wysote, Travis +7 more
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