Results 41 to 50 of about 482,751 (315)

Assessing the Safety and Efficacy of Self-Expanding Metallic Y Stents in a Community Medicine Setting

open access: yesJournal of Respiration
Self-Expanding Metallic (SEM) Y stents are a newer form of stent that is gaining popularity outside the USA, but still has limited data, especially in a community medicine setting.
Daniel Jacob Smith   +5 more
doaj   +1 more source

Noninvasive Solution for Electrochemical Impedance Spectroscopy on Metallic Works of Art [PDF]

open access: yes, 2012
Metallic works of art of cultural relevance are continuously subjected to corrosion as the environment becomes increasingly polluted. A fast and simple method to in situ assess the conservation conditions is therefore required.
Parvis, Marco   +5 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Size-dependent vitrification in metallic glasses

open access: yesNature Communications, 2023
Reducing the sample size can profoundly impact properties of bulk metallic glasses. Here, we systematically reduce the length scale of Au and Pt-based metallic glasses and study their vitrification behavior and atomic mobility.
Valerio Di Lisio   +8 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Mechanisms and Assessment of Genotoxicity of Metallic Engineered Nanomaterials in the Human Environment

open access: yesBiomedicines
Engineered nanomaterials (ENMs) have a broad array of applications in agriculture, engineering, manufacturing, and medicine. Decades of toxicology research have demonstrated that ENMs can cause genotoxic effects on bacteria, mammalian cells, and animals.
Benjamin M. Liu, A. Wallace Hayes
doaj   +1 more source

Fail-safe design of integral metallic aircraft structures reinforced by bonded crack retarders [PDF]

open access: yes, 2009
This paper presents an investigation on the effectiveness of crack growth retarders bonded to integral metallic structures. The study was performed by both numerical modelling and experimental tests.
Irving, Phil E.   +9 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Effect of composition and thermal history on deformation behavior and cluster connections in model bulk metallic glasses

open access: yesScientific Reports, 2022
The compositional dependence and influence of relaxation state on the deformation behavior of a Pt–Pd-based bulk metallic glasses model system was investigated, where platinum is systematically replaced by topologically equivalent palladium atoms.
Nico Neuber   +11 more
doaj   +1 more source

Surgical Classification for Preclinical Rat Femoral Bone Defect Model: Standardization Based on Systematic Review, Anatomical Analysis and Virtual Surgery

open access: yesBioengineering, 2022
Though surgical techniques profoundly influence in vivo experiments, significant heterogeneity exists in current surgeries for inducing rat femoral bone defects. Such variations reduce the reproducibility and comparability of preclinical studies, and are
Yu Sun   +2 more
doaj   +1 more source

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