Results 111 to 120 of about 23,761 (232)

Molecular Investigations on Angiogenesis and Oxidative Stress in Roe Deer (Capreolus capreolus) Bucks' Testes Throughout the Reproductive Cycle

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 4, Page 351-360, May 2026.
ABSTRACT Animals with seasonal reproductive cycles, as the Roe deer (Capreolus capreolus), have developed mechanisms to synchronize reproduction with the environmental cycle in order to optimize reproductive success through melatonin. Angiogenesis and oxidative stress are key processes in spermatogenesis, contributing to testicular remodeling and ...
Ilaria Troisio, Domenico Ventrella, Bálint Lóránt Hausz, Mattia Cesauri, Niccolò Ian Vannetti, Maria Laura Bacci, Alberto Elmi, Augusta Zannoni   +7 more
wiley   +1 more source

Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha, Cristina Maria Turim Santos Miguel, Emília Maria França Lima, Uelinton Manoel Pinto, Cláudia Vieira Prudêncio, Svetoslav Dimitrov Todorov   +5 more
wiley   +1 more source

Generation and modulation of catalytically relevant states of a dye‐decolourizing peroxidase using time‐resolved serial femtosecond crystallography with drop‐on‐chip mixing and X‐ray‐driven reduction

Acta Crystallographica Section D, Volume 82, Issue 5, Page 434-445, May 2026.
We characterize the formation of a ferryl state of a dye‐decolourizing peroxidase by drop‐on‐chip serial femtosecond crystallography and also the modulation of the heme redox state using dose‐resolved serial synchrotron crystallography.Metalloenzymes containing a heme cofactor catalyse a wide range of oxidative reactions critical to life. Understanding
Marina Lučić, Johan Glerup, Pierre Aller, Danny Axford, Nicholas Devenish, Jaehyun Park, Anastasiia Shilova, Arturo Landeros de la Isla, Richard W. Strange, Tiankun Zhou, Robin L. Owen, Jonathan A. R. Worrall, Michael A. Hough   +12 more
wiley   +1 more source

Rational Design of Artificial Metalloproteins and Metalloenzymes with Metal Clusters

Molecules, 2019
Metalloproteins and metalloenzymes play important roles in biological systems by using the limited metal ions, complexes, and clusters that are associated with the protein matrix.
Ying-Wu Lin
doaj   +1 more source

Rapid and Precise Determination of Zero-Field Splittings by Terahertz Time-Domain Electron Paramagnetic Resonance Spectroscopy

, 2017
Zero-field splitting (ZFS) parameters are fundamentally tied to the geometries of metal ion complexes. Despite their critical importance for understanding the magnetism and spectroscopy of metal complexes, they are not routinely available through general
Belvin, Carina, Dincă, Mircea, Gedik, Nuh, Li, Xian, Lu, Jian, Nelson, Keith A., Ofori-Okai, Benjamin K., Ozel, I. Ozge, Skorupskii, Grigorii, Sun, Lei   +9 more
core   +1 more source

Emerging Technologies for Biobutanol Production via Syngas Fermentation

GCB Bioenergy, Volume 18, Issue 5, May 2026.
Biobutanol production from syngas is promising but limited by microbial energy conservation and gas–liquid mass transfer. This review integrates advances in cultivation control and bioreactor engineering with next‐generation biological tools including metabolic rewiring, co‐cultivation and chain elongation, and electro‐fermentation to enable carbon ...
Xuemei Wang, Luiza C. Campos, Zifu Li, Werner Fuchs   +3 more
wiley   +1 more source

Mitochondrial β‐carbonic anhydrase is a conserved metabolic rheostat for branched‐chain amino acid catabolism and metabolic flexibility

New Phytologist, Volume 250, Issue 4, Page 2415-2427, May 2026.
Summary Carbonic anhydrases (CAs) are ubiquitous metalloenzymes that catalyze the reversible hydration of CO2, enabling fundamental processes in organisms across all domains of life. Among all CAs, the role of mitochondrial βCA remains poorly understood. Here, we identify a mitochondrial βCA, βCA6, as a key regulator of branched‐chain amino acid (BCAA)
Naveen Sharma, Thomas D. Sharkey, Federica Brandizzi   +2 more
wiley   +1 more source

Impact of Maternal Helicobacter pylori Infection on Trace Elements (Copper, Iron and Zinc) and Pregnancy Outcomes [PDF]

, 2010
Background: H. pylori infection has been suggested to interfere with micronutrient metabolism and influence pregnancy outcomes. Objectives: This study therefore seeks to document the prevalence of H.
Akubugwo, EI, Ugwuja, EI
core  

Fair and Square: Design, Synthesis and Biological Evaluations of Squaric Acid Derivatives as Novel HDAC8 Inhibitors

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Histone deacetylase 8 (HDAC8) is a clinically validated target in neuroblastoma, where isoform selective inhibition offers a strategy to suppress tumour growth while limiting off‐target toxicity. Hydroxamic acids remain the dominant zinc‐binding group (ZBG) in HDAC inhibitors but are also associated with metabolic instability, suboptimal ...
Nathan Long, Franz‐Josef Meyer‐Almes, Aleksandra Kopranovic, Stephen P. Wren   +3 more
wiley   +1 more source

Effects of vitamin e and zinc supplementation on antioxidants in beta thalassemia major patients [PDF]

, 2011
Objective: In beta thalassemic patients, tissue damage occurs due to oxidative stress and it happens because of the accumulation of iron in the body. This study was conducted to determine the effect of zinc and vitamin E supplementation on antioxidant ...
Aboomardani, M., Arefhosseini, S.-R., Joshaghani, H., Keshtkar, A., Rafraf, M., Rashidi, M.   +5 more
core   +1 more source