Results 111 to 120 of about 21,893 (312)
Serum levels of matrix metalloproteinases-2 and-9 and their tissue inhibitors in inflammatory neuromuscular disorders [PDF]
, 2006 We monitored serum levels of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) before and during intravenously applied immunoglobulin (IVIG) therapy in 33 patients with chronic immune-mediated neuropathies and myopathies and 15 ...
B.G.H. Schoser +15 more
core +1 more source
Nature Reviews Chemistry, 2021 Matthew J. Chalkley, S. Mann, W. DeGrado
semanticscholar +1 more source
Force-induced chemical reactions on the metal centre in a single metalloprotein molecule
Nature Communications, 2015 Metalloproteins play indispensable roles in biology owing to the versatile chemical reactivity of metal centres. However, studying their reactivity in many metalloproteins is challenging, as protein three-dimensional structure encloses labile metal ...
Peng Zheng +3 more
semanticscholar +1 more source
Cell Proliferation, EarlyView.Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li +10 more
wiley +1 more source
EPR of Co(II) as a Structural and Mechanistic Probe of Metalloprotein Active Sites: A Review of Studies on Aminopeptidase [PDF]
, 2002 Co(II) can often be substituted for Zn(II) in zinc-dependent metalloenzymes to provide spectroscopically accessible forms of the enzymes. Co(II) is an excellent spectroscopic probe as it is both optically active and EPR active.
Bennett, Brian
core +1 more source
Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome following Experimental Subarachnoid Hemorrhage [PDF]
, 2011 Background: Cerebral edema is an important risk factor for death and poor outcome following subarachnoid hemorrhage (SAH). However, underlying mechanisms are still poorly understood.
Bauer AT +29 more
core +1 more source
Experimental Physiology, EarlyView.Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto +10 more
wiley +1 more source
Electrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making
Scientific Reports, 2015 We demonstrate an analog type logical device that combines metalloprotein and organic/inorganic materials and can make an interactive analog decision.
Yongho Chung +4 more
semanticscholar +1 more source
Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning
The FASEB Journal, Volume 39, Issue 12, 30 June 2025.Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley +1 more source