Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV [PDF]
, 2019 The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies.
Díaz Moreno, Irene +4 more
core +1 more source
An artificial CO-releasing metalloprotein built by histidine-selective metallation.
Chemical Communications, 2015 We report the design and synthesis of an aquacarbonyl Ru(II) dication cis-[Ru(CO)2(H2O)4](2+) reagent for histidine (His)-selective metallation of interleukin (IL)-8 at site 33.
Inês S Albuquerque +6 more
semanticscholar +1 more source
Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]
, 2016 The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela +5 more
core +1 more source
Force-induced chemical reactions on the metal centre in a single metalloprotein molecule
Nature Communications, 2015 Metalloproteins play indispensable roles in biology owing to the versatile chemical reactivity of metal centres. However, studying their reactivity in many metalloproteins is challenging, as protein three-dimensional structure encloses labile metal ...
Peng Zheng +3 more
semanticscholar +1 more source
Electrochemical Bioelectronic Device Consisting of Metalloprotein for Analog Decision Making
Scientific Reports, 2015 We demonstrate an analog type logical device that combines metalloprotein and organic/inorganic materials and can make an interactive analog decision.
Yongho Chung +4 more
semanticscholar +1 more source
Effect of ELF e.m. fields on metalloprotein redox-active sites
, 2007 The peculiarity of the distribution and geometry of metallic ions in enzymes pushed us to set the hypothesis that metallic ions in active-site act like tiny antennas able to pick up very feeble e.m. signals.
Badon, T. +6 more
core
Metalloproteomics: Principles, challenges and applications to neurodegeneration
Frontiers in Aging Neuroscience, 2013 Trace elements are required for a variety of normal biological functions. As our understanding of neurodegenerative disease advances we are identifying a number of metalloenzymes involved in disease process.
Blaine Russell Roberts +6 more
doaj +1 more source
Surface Immobilized His-tagged Azurin as a Model Interface for the Investigation of Vectorial Electron Transfer in Biological Systems [PDF]
, 2015 A model system for the electrochemical investigation of vectorial electron transfer in biological systems was designed, assembled and characterized. Gold electrodes, functionalized with a -OCH3 terminated, aromatic self-assembled monolayer, were used as ...
Berto, Marcello +9 more
core +1 more source
Studies on the conformational changes of metalloproteins induced by electrons in water—ethylene glycol solutions at low temperatures. Cytochrome C [PDF]
, 1974 Lev Blumenfeld +4 more
openalex +1 more source
‘Unconventional’ Coordination Chemistry by Metal Chelating Fragments in a Metalloprotein Active Site
Journal of the American Chemical Society, 2014 The binding of three closely related chelators: 5-hydroxy-2-methyl-4H-pyran-4-thione (allothiomaltol, ATM), 3-hydroxy-2-methyl-4H-pyran-4-thione (thiomaltol, TM), and 3-hydroxy-4H-pyran-4-thione (thiopyromeconic acid, TPMA) to the active site of human ...
David P. Martin +7 more
semanticscholar +1 more source