Results 121 to 130 of about 21,893 (312)

Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin

STAR Protocols, 2022
Summary: Keyhole limpet hemocyanin (KLH) is a glycosylated multi-subunit metalloprotein that elicits a strong nonspecific immune activation, thus inducing both cellular and humoral immune responses.
Léa Montégut, Hui Chen, José Manuel Bravo-San Pedro, Omar Motiño, Isabelle Martins, Guido Kroemer   +5 more
doaj  

Development of a New AMBER Force Field for Cysteine and Histidine Cadmium‐Binding Proteins and Its Validation Through QM/MM MD Simulations

Journal of Computational Chemistry, Volume 46, Issue 16, June 15, 2025.
In the context of the AMBER parameterization, a new force field is developed and validated for the simulation of cadmium(II)‐binding proteins. The proposed force field takes into account the polarization effect produced by the central ion on its surroundings.
Matteo Orlandi, Marina Macchiagodena, Piero Procacci, Fabrizio Carta, Claudiu T. Supuran, Marco Pagliai   +5 more
wiley   +1 more source

Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]

, 2015
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S, De Carlo, D, Fineschi, Vittorio, Fiore, C, Neri, M, Riezzo, I, Turillazzi, E   +6 more
core   +1 more source

The Arabidopsis cysteine-rich GASA5 is a redox-active metalloprotein that suppresses gibberellin responses.

Molecular Plant, 2014
Dear Editor, The plant-specific GIBBERELLIN (GA)-STIMULATED TRANSCRIPT 1 (GAST1)-like genes have been identified in numerous plant species and many of them are regulated by the phytohormone GA.All encode small proteins with a conserved cysteine-rich C ...
L. Rubinovich, S. Ruthstein, D. Weiss
semanticscholar   +1 more source

The Energetics of Electron Transfer in Redox‐DNA Layers Mimics That of Redox Proteins

Chemistry – A European Journal, Volume 31, Issue 33, June 12, 2025.
The electron transfer in ferrocene‐labeled DNA (Fc‐DNA) layers mimics that of redox proteins, featuring a low reorganization energy (λ). The origin of the low λ in Fc‐DNA was unveiled by high‐scan‐rate cyclic voltammetry and molecular dynamics simulations, implying Fc‐DNA as a versatile tool to open new avenues in understanding the ET in biological ...
Zhiyong Zheng, Simon Grall, Soo Hyeon Kim, Arnaud Chovin, Nicolas Clement, Christophe Demaille   +5 more
wiley   +1 more source

Imaging of compartmentalised intracellular nitric oxide, induced during bacterial phagocytosis, using a metalloprotein–gold nanoparticle conjugate [PDF]

, 2017
Nitric oxide (NO) plays an essential role within the immune system since it is involved in the break-down of infectious agents such as viruses and bacteria.
Gavrilovic, Jelena, Leggett, Richard, Marín, Maria J., Russell, David A., Thomas, Paul   +4 more
core   +1 more source

Metalloproteomics: Principles, challenges and applications to neurodegeneration

Frontiers in Aging Neuroscience, 2013
Trace elements are required for a variety of normal biological functions. As our understanding of neurodegenerative disease advances we are identifying a number of metalloenzymes involved in disease process.
Blaine Russell Roberts, Amber eLothian, Dominic James Hare, Dominic James Hare, Colin L. Masters, Timothy M. Ryan, Rudolf eGrimm   +6 more
doaj   +1 more source

The Role of Asparagine as a Gatekeeper Residue in the Selective Binding of Rare Earth Elements by Lanthanide‐Binding Peptides

Chemistry – A European Journal, Volume 31, Issue 33, June 12, 2025.
Lanthanide binding tags (LBTs) have been utilized as a green extractant to selectively separate rare earth elements (REEs). We reveal up from the molecular level how the N5 asparagine residue is indispensable in imparting selective complexation between lighter and heavier lanthanides by conformationally functioning as a gate.
Surabh S. KT, Baofu Qiao, Jason G. Marmorstein, Yiming Wang, Denize C. Favaro, Kathleen J. Stebe, E. James Petersson, Ravi Radhakrishnan, Cesar de la Fuente‐Nunez, Raymond S. Tu, Charles Maldarelli, Monica Olvera de la Cruz, Robert J. Messinger   +12 more
wiley   +1 more source

Metalloprotein-based electronic nanodevices [PDF]

, 2006
A key challenge of the current research in nanoelectronics is the realization of biomolecular devices. The use of electron-transfer proteins, such as the blue copper protein, azurin (Az), is particularly attractive because of its natural redox properties and self-assembly capability.
RINALDI, Rosaria, MARUCCIO, Giuseppe, BIASCO, Adriana Lucia Angela, POMPA, Pier Paolo, A. Bramanti, ARIMA, VALENTINA, VISCONTI, Paolo, D'AMICO, STEFANO, E. D'Amone, CINGOLANI, Roberto   +9 more
openaire   +5 more sources

Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy.

Journal of the American Chemical Society, 2013
Genetically encoded unnatural amino acids could facilitate the design of proteins and enzymes of novel function, but correctly specifying sites of incorporation and the identities and orientations of surrounding residues represents a formidable challenge.
J. Mills, S. Khare, J. Bolduc, F. Forouhar, V. Mulligan, S. Lew, J. Seetharaman, L. Tong, B. Stoddard, David Baker   +9 more
semanticscholar   +1 more source