Results 131 to 140 of about 21,893 (312)
ChemBioChem, Volume 26, Issue 11, June 3, 2025.In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout +1 more
wiley +1 more source
Studies on the conformational changes of metalloproteins induced by electrons in water—ethylene glycol solutions at low temperatures. Cytochrome C [PDF]
, 1974 Lev Blumenfeld +4 more
openalex +1 more source
‘Unconventional’ Coordination Chemistry by Metal Chelating Fragments in a Metalloprotein Active Site
Journal of the American Chemical Society, 2014 The binding of three closely related chelators: 5-hydroxy-2-methyl-4H-pyran-4-thione (allothiomaltol, ATM), 3-hydroxy-2-methyl-4H-pyran-4-thione (thiomaltol, TM), and 3-hydroxy-4H-pyran-4-thione (thiopyromeconic acid, TPMA) to the active site of human ...
David P. Martin +7 more
semanticscholar +1 more source
Designing Enzymatic Reactivity with an Expanded Palette
ChemBioChem, Volume 26, Issue 11, June 3, 2025.Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley +1 more source
Probing metalloproteins by voltammetry [PDF]
, 2006 Dynamic electrochemical methods, which have long held an important place among the techniques of the coordination chemist, have generally remained unexploited by those seeking to understand the complex and often elusive chemistry of metal centres in proteins.
openaire +2 more sources
Proton NMR Spectroscopy as a Probe of Dinuclear Copper(II) Active Sites in Metalloproteins. Characterization of the Hyperactive Copper(II)-Substituted Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]
, 1998 Proton NMR spectra of the hyperactive Cu(II)-substituted aminopeptidase from Aeromonas proteolytica (AAP) were recorded in both H2O and D2O buffered solution at pH 6.7.
Bennett, Brian +3 more
core +1 more source
The Study Of The Levels Of Metalloproteinases, Cytokines And Lymphocyte Activation Markers In Seminal Plasma Of Men, Depending On Fertility [PDF]
, 2018 The study of the concentration of metalloproteinases, pro- and anti-inflammatory cytokines, lymphocyte activation markers in seminal plasma of men with oligosymptomatic forms of chronic inflammation of the urogenital tract (CIUT), depending on the ...
Matyucha, L. (Larysa) +1 more
core +2 more sources
Nature CommunicationsMaturation of iron-sulfur proteins in eukaryotes is initiated in mitochondria by the core iron-sulfur cluster assembly (ISC) complex, consisting of the cysteine desulfurase sub-complex NFS1-ISD11-ACP1, the scaffold protein ISCU2, the electron donor ...
Vinzent Schulz +10 more
doaj +1 more source
Frontiers in Chemistry, 2018 Quantum mechanical approaches for the massive computation on large biological system such as virtual screening in drug design and development have presented a challenge to computational chemists for many years.
Mingsong Shi, Dingguo Xu, Jun Zeng
doaj +1 more source
Engineered Tissue Models to Decode Host–Microbiota Interactions
Advanced Science, Volume 12, Issue 23, June 20, 2025.Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio +5 more
wiley +1 more source