GA: Bioprinting‐assisted tissue assembly, a method for generating versatile and complex tissue constructs, is employed to investigate the contribution of endothelial cells (ECs) in cardiac fibrosis. ECs modulate fibrotic responses not only by preventing significant tissue stiffening and contractile impairment but also by exhibiting endothelial‐to ...
Dong Gyu Hwang+6 more
wiley +1 more source
The rs243865 Polymorphism in Matrix Metalloproteinase-2 and its Association With Target Organ Damage in Patients With Resistant Hypertension: Cross-Sectional Study. [PDF]
Tuan Huynh A+4 more
europepmc +1 more source
Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou+4 more
wiley +1 more source
The Missing Enzymes: A Call to Update Pharmacological Profiling Practices for Better Drug Safety Assessment. [PDF]
Maciag M, Karamyan VT.
europepmc +1 more source
Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling [PDF]
Jane Ashworth+6 more
openalex +1 more source
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli+3 more
wiley +1 more source
MMP-9 metalloproteinase and its regulator are not associated with mid-term CT residual abnormalities in patients with COVID-19 pneumonia. [PDF]
Mattone M+6 more
europepmc +1 more source
Different Susceptibilities of Fibulin-1 and Fibulin-2 to Cleavage by Matrix Metalloproteinases and Other Tissue Proteases [PDF]
Takako Sasaki+4 more
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Functional Synovium‐Based 3D Models in the Context of Human Disease and Inflammation
The synovium is key to joint function but is often affected by diseases like rheumatoid arthritis. Finding better treatments is challenging because current lab models do not fully mimic real tissues. New 3D technologies, like bioprinting, offer better methods to study these diseases, improve drug testing, and develop personalized treatments, bringing ...
Amelia Heslington+3 more
wiley +1 more source