Results 161 to 170 of about 182,335 (266)

Effects of P38 MAPK Pathway Inhibition on the Metabolism of Periodontal Ligament Fibroblasts During Inflammation. [PDF]

J Cell Mol Med
Qian C, Gu Y, Gao F, Xu Z, Li J, Liu S, He R, Zhong L, Wang J.   +8 more
europepmc   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Elevated serum levels of interleukin-11 and matrix metalloproteinase-9 in myalgic encephalomyelitis/chronic fatigue syndrome. [PDF]

Front Immunol
Chinnappan B, Kempuraj D, Aenlle KK, Middleton A, Day KS, Kothuru SP, Joshi RS, Klimas NG, Theoharides TC.   +8 more
europepmc   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Blood biomarkers and atrial remodeling in patients at risk of atrial fibrillation. [PDF]

Front Mol Med
Loncaric F, Forado Benatar I, Mimbrero Guillamon M, Nunno L, Jimenez-Arjona R, Tirapu L, Montserrat S, Sanchis L, Doltra A, Bijnens B, Sitges M.   +10 more
europepmc   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

The causal effect of matrix metalloproteinase 9 on interstitial lung disease risk mediated by effector memory double negative T cells: A mediation Mendelian randomization study. [PDF]

Medicine (Baltimore)
Ren Q, Sun F, Yang L, Su D, Shen M.
europepmc   +1 more source

Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum

Clinical Anatomy, EarlyView.
ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery, Andrew C. Hall, Thomas H. Gillingwater, Afaf Alsolami, Abduelmenem Alashkham   +4 more
wiley   +1 more source

Prognostic Value of Serum MMP9 in Predicting Mortality Among Elderly Patients with Sepsis: A Prospective Cohort Study. [PDF]

J Inflamm Res
Yan F, Liu T, Yuan L, Qiu Y, Huang S, Zhang L, Bai W, Zhang C, Peng X, Yang Y, Wang F.   +10 more
europepmc   +1 more source

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

Chemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma, Peter A. C. Wing, Wojtek Treyde, Shyam Basak, Simeon D. Draganov, Taylah Andrews‐Clark, Eidarus Salah, Petra Lukacik, Claire Strain‐Damerell, Adán Pinto‐Fernández, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield, Lennart Brewitz   +13 more
wiley   +1 more source