Myo-inflam: a mini review on inflammatory pathways driving scleral remodeling and axial elongation. [PDF]
Front ImmunolLin B, Liang W, Cai LR, Xu M, Li DK.
europepmc +1 more source
Chemistry – A European Journal, EarlyView.Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt +3 more
wiley +1 more source
The Role of Matrix Metalloproteinases in Orthodontics, Dental Trauma, Restorative Dentistry, and Endodontics: Molecular Mechanisms and Clinical Implications. [PDF]
Int J Mol SciŁawicka R +6 more
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Secretopathies emerge as a new class of neurocristopathies
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
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Serum matrix metalloproteinase-7 as a diagnostic and prognostic biomarker in primary biliary cholangitis. [PDF]
Front Med (Lausanne)Chen J +6 more
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Drosophila male genitalia rotation depends on permissive remodeling of the posterior abdomen
Developmental Dynamics, EarlyView.Abstract Background One of the most characteristic morphogenetic processes in Drosophila is the 360° rotation of the male pupal genital disc. This movement is driven by the myosin Myo1D, whose expression in the genital disc is controlled by the Hox gene Abdominal‐B (Abd‐B).
Nuria Prieto +6 more
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Exploring the significance of EGFR, MMP-2, MMP-9, HIF-1α, and CAIX as molecular biomarkers in ocular surface squamous neoplasia. [PDF]
Indian J Med ResRamachandran RG +4 more
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Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
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Maternal Infection Impairs Motor Coordination in an Experimental Meningitis Rat Model Through Altered MMP-2/3/9 Activity, H3K4 Trimethylation, and <i>Reln</i> Methylation. [PDF]
Int J Mol SciSurya TS +4 more
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Biomarkers of lung congestion and injury in acute heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
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