Results 51 to 60 of about 125,457 (165)

Matrilysins and Stromelysins in Pathogenesis and Diagnostics of Cancers

Cancer Management and Research, 2020
Barbara Maria Piskór,1 Andrzej Przylipiak,1 Emilia Dąbrowska,1 Marek Niczyporuk,1 Sławomir Ławicki2 1Department of Aesthetic Medicine, Medical University of Bialystok, Bialystok, Poland; 2Department of Population Medicine and Civilization Diseases
Piskór BM, Przylipiak A, Dąbrowska E, Niczyporuk M, Ławicki S   +4 more
doaj  

The modern concept of wound healing in glaucoma surgery

Oftalʹmologiâ, 2016
Post-operative wound healing is one of the key-factors, defining success of filtrating surgery in late post-operative period. Wound healing is a physiological response directed at tissue structure reconstruction and function restoration, performed by ...
S. Yu. Petrov, D. M. Safonova
doaj   +1 more source

Expression of Matrix Metalloproteinase, a Disintegrin and Metalloproteinase, and Tissue Inhibitor of Metalloproteinase in Human Chondrosarcoma

ACTA HISTOCHEMICA ET CYTOCHEMICA, 2004
Malignant degree of human chondrosarcoma can be difficult to determine using only histological findings. We therefore assessed expression of matrix metalloproteinases (MMPs), a disintegrin and metalloproteinase (ADAM) with thrombospondin motifs (ADAMTSs) and tissue inhibitor of metalloproteinases (TIMPs) in chondrosarcoma and ascertained relationships ...
Sugita, Hideyuki, Osaka, Shunzo, Toriyama, Masato, Osaka, Eiji, Yoshida, Yukihiro, Ryu, Junnosuke, Sano, Makoto, Sugitani, Masahiko, Nemoto, Norimichi   +8 more
openaire   +2 more sources

Matrix metalloproteinases and epileptogenesis [PDF]

Molecular and Cellular Pediatrics, 2014
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
openaire   +2 more sources

Role of laminin bioavailability in the astroglial permissivity for neuritic outgrowth

Anais da Academia Brasileira de Ciências, 2002
The mechanisms involved in the failure of an adult brain to regenerate post-lesion remain poorly understood. The reactive gliosis which occurs after an injury to the CNS and leads to the glial scar has been considered as one of the major impediments to ...
TARDY MARCIENNE
doaj  

Matrix Metalloproteinase Inhibitors and Their Potential Clinical Application in Periodontitis

Diseases
Matrix metalloproteinases (MMPs) are a family of endopeptidases recognized for their involvement in the degradation of the extracellular matrix and their important role in the pathogenesis of periodontitis.
Daniela Mendoza-Juárez, Manuel Sánchez-Gutiérrez, Aleli Julieta Izquierdo-Vega, Eduardo Osiris Madrigal-Santillán, Claudia Velázquez-González, Jeannett Alejandra Izquierdo-Vega   +5 more
doaj   +1 more source

Hyperglycemia Suppresses Calcium Phosphate–Induced Aneurysm Formation Through Inhibition of Macrophage Activation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe aim of this study was to elucidate aspects of diabetes mellitus–induced suppression of aneurysm. We hypothesized that high glucose suppresses aneurysm by inhibiting macrophage activation via activation of Nr1h2 (also known as liver X ...
Teruyoshi Tanaka, Yuichiro Takei, Dai Yamanouchi   +2 more
doaj   +1 more source

Longitudinal trajectories of hematological indices and serum metalloproteinases-2 and 9 over 1 year after moderate and severe COVID-19

Frontiers in Medicine
IntroductionThe long-term clinical burden of Coronavirus disease (COVID-19) remains substantial, yet one-year cohort evidence linking blood-based biomarkers to persistent sequelae is limited.MethodsWe conducted a longitudinal study in adults aged 18–80 ...
Rebecca Salomão, Gabriel Pasquarelli-do-Nascimento, Mayara Ananias, Victoria Assis, Leandro Gomes de Jesus Ferreira, Leandro Gomes de Jesus Ferreira, Isabella da Silva Almeida, Isabella da Silva Almeida, Leandra Silva, Katiane Tostes, Bruna Pereira Sorroche, Lidia Maria Rebolho Batista Arantes, Kelly Grace Magalhães, Liliana Torcoroma García, Rochelle Rocha Costa, João Luiz Quagliotti Durigan, João Luiz Quagliotti Durigan, Rita de Cássia Marqueti, Rita de Cássia Marqueti   +18 more
doaj   +1 more source

Inhibition of Metalloproteinases Extends Longevity and Function of In Vitro Human iPSC-Derived Skeletal Muscle

Biomedicines
In vitro culture longevity has long been a concern for disease modeling and drug testing when using contractable cells. The dynamic nature of certain cells, such as skeletal muscle, contributes to cell surface release, which limits the system’s ability ...
Natali Barakat, Himanshi Jangir, Leandro Gallo, Marcella Grillo, Xiufang Guo, James Hickman   +5 more
doaj   +1 more source

Direct Fibrinolytic Snake Venom Metalloproteinases Affecting Hemostasis: Structural, Biochemical Features and Therapeutic Potential

Toxins, 2017
Snake venom metalloproteinases (SVMPs) are predominant in viperid venoms, which provoke hemorrhage and affect hemostasis and thrombosis. P-I class enzymes consist only of a single metalloproteinase domain.
Eladio F. Sanchez, Renzo J. Flores-Ortiz, Valeria G. Alvarenga, Johannes A. Eble   +3 more
doaj   +1 more source