Results 31 to 40 of about 32,940 (209)

Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]

, 2012
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Elfriede Noessner, Susan Notohamiprodjo, Pankaj Goyal, Sauter, M., Sitter, T., Sitter, Thomas, Markus Wörnle, Andrea Ribeiro, Peter J. Nelson (168215), Thomas Sitter, Matthias Sauter (168187), Wolfgang Siess, Wolfgang Siess (168198), Susanne Himmelein, Nelson, P.J., Himmelein, Susanne, Thomas Sitter (168211), Goyal, P., Sauter, Matthias, Susanne Himmelein (168206), Nelson, Peter J., Markus Wörnle (168201), Susan Notohamiprodjo (168192), Ribeiro, A., Notohamiprodjo, Susan, Elfriede Noessner (146689), Noessner, Elfriede, Wörnle, Markus, Djafarzadeh, Roghieh, Roghieh Djafarzadeh, Matthias Sauter, Nößner, E., Andrea Ribeiro (168203), Roghieh Djafarzadeh (88033), Himmelein, S., Peter J Nelson, Wörnle, M., Goyal, Pankaj, Ribeiro, Andrea, Djafarzadeh, R., Notohamiprodjo, S., Pankaj Goyal (156516), Siess, W., Siess, Wolfgang   +43 more
core   +2 more sources

Combined Radiochemotherapy: Metalloproteinases Revisited [PDF]

, 2021
Besides cytotoxic DNA damage irradiation of tumor cells triggers multiple intra- and intercellular signaling processes, that are part of a multilayered, treatment-induced stress response at the unicellular and tumor pathophysiological level.
Pruschy, Martin, Waller, Verena
core   +1 more source

Allelic and Genotypic Distribution of MMP13-77 A/G Polymorphism in Salvadoran Children With and Without Caries

Clinics and Practice
Background/Objectives: Polymorphisms in metalloproteinases (MMPs) have the potential to be probable genetic biomarkers of dental caries. The aim of this study was to evaluate the distribution of the MMP13 A/G rs2252070 single nucleotide polymorphism (SNP)
Wendy Escobar-González, Jorge Alegría-Torres, Yolanda Terán-Figueroa, Vianney Castañeda-Monroy, Aurelio Álvarez-Vargas, Carlo Eduardo Medina-Solís, Nuria Patiño-Marín   +6 more
doaj   +1 more source

Perfil de proteases de lesões cutâneas experimentais em camundongos tratadas com a lectina isolada das sementes de Canavalia brasiliensis Proteases profile of skin wounds treated with lectin from Canavalia brasiliensis seeds

Ciência Rural, 2009
O objetivo deste estudo foi determinar o perfil de proteases em lesões cutâneas experimentais tratadas com a lectina isolada das sementes da Canavalia brasiliensis (ConBr) livre e conjugada com o seu açúcar específico.
Flávio de Oliveira Silva, Rosângela Vidal de Souza Araújo, Giuliana Viegas Schirato, Edson Holanda Teixeira, Mário Ribeiro de Melo Júnior, Benildo de Sousa Cavada, José Luiz de Lima-Filho, Ana Maria dos Anjos Carneiro-Leão, Ana Lúcia Figueiredo Porto   +8 more
doaj   +1 more source

Association Between Plasma ADAMTS-7 Levels and Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus

Medicina
A disintegrin and metalloproteinase with thrombospondin motifs-7 (ADAMTS-7) belongs to the family of metalloproteinases that contributes to tissue homeostasis during morphogenesis and reproduction. These metalloproteinases regulate various cell functions
Asimina Ganotopoulou, Emmanouil Korakas, Loukia Pliouta, Aikaterini Kountouri, Sotirios Pililis, Stamatios Lampsas, Ignatios Ikonomidis, Loukianos S. Rallidis, Athanasia Papazafiropoulou, Andreas Melidonis, Vaia Lambadiari   +10 more
doaj   +1 more source

Lonidamine Causes Inhibition of Angiogenesis-Related Endothelial Cell Functions

Neoplasia: An International Journal for Oncology Research, 2004
The aim of this study was to assess whether lonidamine (LND) interferes with some steps in angiogenesis progression. We report here, for the first time, that LND inhibited angiogenic-related endothelial cell functions in a dose-dependent manner (1-50 μg ...
Donatella Del Bufalo, Daniela Trisciuoglio, Marco Scarsella, Giulia D'Amati, Antonio Candiloro, Angela Iervolino, Carlo Leonetti, Gabriella Zupi   +7 more
doaj   +1 more source

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

Toxins, 2021
A global strategy, under the coordination of the World Health Organization, is being unfolded to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure safe and effective treatments.
José María Gutiérrez, Laura-Oana Albulescu, Rachel H. Clare, Nicholas R. Casewell, Tarek Mohamed Abd El-Aziz, Teresa Escalante, Alexandra Rucavado   +6 more
doaj   +1 more source

A Strong Decrease in TIMP3 Expression Mediated by the Presence of miR-17 and 20a Enables Extracellular Matrix Remodeling in the NSCLC Lesion Surroundings

Frontiers in Oncology, 2019
Background: Lung cancer is one of the most common causes of death worldwide with a relatively high fatality rate and a mean 5-years survival of about 18%.
Karolina H. Czarnecka, Karolina H. Czarnecka, Bartosz Szmyd, Magda Barańska, Marcin Kaszkowiak, Jacek Kordiak, Adam Antczak, Dorota Pastuszak-Lewandoska, Ewa Brzeziańska-Lasota   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Intracellular trafficking and secretion of matrix metalloproteinases during macrophage migration [PDF]

, 2016
This thesis advances the knowledge of intracellular trafficking pathways for the cell surface delivery of Matrix metalloproteinases 9 and 14 in macrophages.
Rohl, Joan
core   +1 more source