Testing the limits: serial crystallography using unpatterned fixed targets
IUCrJSheet-on-sheet (SOS) fixed-target chips are arguably the most versatile, cheapest and simplest sample-delivery method for ambient-temperature data acquisition using serial crystallography approaches at synchrotrons and X-ray free-electron lasers (XFELs).
Alexander Gorel +12 more
doaj +1 more source
Ultrasensitive Detection of FKBP12 Using a Synthetic Receptor‐Functionalized QCM Nanoplatform
Advanced Sensor Research, Volume 4, Issue 10, October 2025.A reusable nanosensor platform for ultralow FKBP12 detection in physiological fluids is presented. Combining a gold‐coated QCM with a custom‐designed receptor in a self‐assembled monolayer, the device achieves picomolar sensitivity and high selectivity.
Martina Tozzetti +8 more
wiley +1 more source
Bioavailability of Metal Ions and Evolutionary Adaptation
Life, 2012 The evolution of life on earth has been a long process that began nearly 3,5 x 109 years ago. In their initial moments, evolution was mainly influenced by anaerobic environments; with the rise of O2 and the corresponding change in bioavailability of ...
Rolando P. Hong Enriquez, Trang N. Do
doaj +1 more source
Isolated Heme A Synthase from
mBio, 2020 The integral membrane protein heme A synthase (HAS) catalyzes the biosynthesis of heme A, which is a prerequisite for cellular respiration in a wide range of aerobic organisms.
Hui Zeng +9 more
doaj +1 more source
Mitomycin C Induces Autophagy in Human Tracheal Fibroblasts and Suppresses Their Growth
Laryngoscope Investigative Otolaryngology, Volume 10, Issue 5, October 2025.Mitomycin C (MMC) selectively inhibits the proliferation of human tracheal fibroblasts (hTF) more effectively than human tracheal epithelial cells (hTEC), with hTF showing a dose‐ and time‐dependent sensitivity to MMC treatment. Additionally, MMC induces autophagy in hTF, as evidenced by increased expression of autophagy markers, while suppressing cell
Jeong‐Mi Kim +5 more
wiley +1 more source
Structure and Dynamics of Metalloproteins in Live Cells [PDF]
, 2008 X-ray absorption spectroscopy (XAS) has emerged as one of the premier tools for investigating the structure and dynamic properties of metals in cells and in metal containing biomolecules. Utilizing the high flux and broad energy range of X-rays supplied
Cook, Jeremy D. +2 more
core +2 more sources
Optimizing Agronomic Zinc Biofortification in Carrots
Plant-Environment Interactions, Volume 6, Issue 5, October 2025.Through optimized application methods, rates, and timing, zinc biofortification in carrots significantly enhances growth, yield, and nutrient accumulation. Foliar application at 6 kg ha−1 zinc increased shoot zinc concentration by 51% compared to soil application, while early application (30 days after sowing) boosted root zinc levels by 175%.
Godfred Okyere‐Prah +7 more
wiley +1 more source
Sculpting Metal‐binding Environments in De Novo Designed Three‐helix Bundles [PDF]
, 2015 De novo protein design is a biologically relevant approach used to study the active centers of native metalloproteins. In this review, we will first discuss the design process in achieving α3D, a de novo designed three‐helix bundle peptide with a well ...
Armitage +68 more
core +1 more source
Cytochrome c signalosome in mitochondria [PDF]
, 2011 Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life is governed by transient electron transfer interactions of cytochrome c inside the mitochondria, the cytoplasmic adducts of cytochrome
Díaz Moreno, Irene +3 more
core +1 more source
The synthesis and characterization of new higher nuclearity arene-ruthenium-sulfur clusters : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Chemistry at Massey University, New Zealand [PDF]
, 1999 This thesis describes a project investigating the synthesis and characterization of new higher nuclearity arene-ruthenium-sulfur clusters and arene-ruthenium-nitrogen complexes.
Guo, Libei
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