Results 101 to 110 of about 27,575 (332)

Mercury and selenium binding biomolecules in terrestrial mammals (Cervus elaphus and Sus scrofa) from a mercury exposed area [PDF]

, 2017
Acknowledgements The authors are grateful to Junta de Comunidades de Castilla-La Mancha (PCC-05-004-2, PAI06-0094, PCI-08-0096, PEII09-0032-5329) and the Ministerio de Economía y Competitividad (CTQ2013-48411-P) for financial support. M.J.
Fariñas, N. Rodríguez, Krupp, E., Martín-Doimeadiosa, R. C. Rodríguez, Matteo, R., Nevado, J. J. Berzas, Ropero, M. J. Patiño   +5 more
core   +1 more source

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

Med Research, EarlyView.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li, Yuxuan Wan, Alan Jiao, Ke Jiang, Gaoyuan Cui, Jinxin Tang, Simin Yu, Zhengang Hu, Songfeng Zhao, Zhenjie Yi, Lifu Long, Yang Yang, Xuehao Cui, Chunrun Qu   +13 more
wiley   +1 more source

Transition metals at the host-pathogen interface: how Neisseria exploit human metalloproteins for acquiring iron and zinc.

Essays in Biochemistry, 2017
Transition metals are essential nutrients for all organisms and important players in the host-microbe interaction. During bacterial infection, a tug-of-war between the host and microbe for nutrient metals occurs: the host innate immune system responds to
W. Neumann, Rose C. Hadley, Elizabeth M. Nolan   +2 more
semanticscholar   +1 more source

Effect of ELF e.m. fields on metalloprotein redox-active sites [PDF]

arXiv, 2008
The peculiarity of the distribution and geometry of metallic ions in enzymes pushed us to set the hypothesis that metallic ions in active-site act like tiny antennas able to pick up very feeble e.m. signals. Enzymatic activity of Cu2+, Zn2+ Superoxide Dismutase (SOD1) and Fe2+ Xanthine Oxidase (XO) has been studied, following in vitro generation and ...
arxiv  

Redox Entropy of Plastocyanin: Developing a Microscopic View of Mesoscopic Polar Solvation [PDF]

, 2007
We report applications of analytical formalisms and Molecular Dynamics (MD) simulations to the calculation of redox entropy of plastocyanin metalloprotein in aqueous solution. The goal of our analysis is to establish critical components of the theory required to describe polar solvation at the mesoscopic scale.
arxiv   +1 more source

Endopeptidase Regulation as a Novel Function of the Zur-Dependent Zinc Starvation Response

mBio, 2019
The cell wall is a strong, yet flexible, meshwork of peptidoglycan (PG) that gives a bacterium structural integrity. To accommodate a growing cell, the wall is remodeled by both PG synthesis and degradation.
Shannon G. Murphy, Laura Alvarez, Myfanwy C. Adams, Shuning Liu, Joshua S. Chappie, Felipe Cava, Tobias Dörr   +6 more
doaj   +1 more source

A minimalist chemical model of matrix metalloproteinases- Can small peptides mimic the more rigid metal binding sites of proteins? [PDF]

, 2013
In order to develop a minimalist chemical model of matrix metalloproteinases (MMPs), we synthesized a pentadecapeptide (Ac-KAHEFGHSLGLDHSK-NH2) corresponding to the catalytic zinc(II) binding site of human MMP-13.
Aguilar, Attila Jancsó, Beck, Burns, Camerman, Daignault, Dávid Árus, Farkas, Farkas, Gajda, Grossoehme, Harford, Heitzer, Högfeldt, Jancsó, Jancsó, Kaiser, Khairy, Kimura, Koike, Kolozsi, Kállay, Massova, Millhauser, Mylonas, Mylonas, Nóra Veronika Nagy, Paksi, Rabenstein, Rajkovic, Rockenbauer, Rosotti, Róbert Berkecz, Stanczak, Sternlicht, Sóvágó, Tallant, Tamás Gajda, Valensin, Valensin, Valensin, Verma, Witkowska, Zastrow, Zoroddu, Zékány, Ágnes Dancs, Árus, Ősz   +48 more
core   +1 more source

Extracting Trends From NMR Data With TrAGICo: A Python Toolbox

Magnetic Resonance in Chemistry, EarlyView.
TrAGICo is a Python collection of functions for the extraction and analysis of serial NMR spectroscopy data. In this tutorial, we show several practical examples, highlighting its utility for various chemical NMR applications, such as extraction of the chemical shift temperature dependence in paramagnetic systems, relaxation studies, and reaction ...
Letizia Fiorucci, Francesco Bruno, Leonardo Querci, Adam Kubrak, Jlenia Bindi, Nebojša Rodić, Giulia Licciardi, Enrico Luchinat, Giacomo Parigi, Mario Piccioli, Enrico Ravera   +10 more
wiley   +1 more source

Electrochemistry of metalloproteins

, 1985
The direct (unmediated) electrochemistry of a variety of redox proteins has been studied at a range of electrode materials. Electrochemical studies using cytochromes, iron-sulphur proteins and copper proteins show a marked enhancement of the heterogeneous electron-transfer rate at the "edge" plane of pyrolytic graphite. Parallel ESCA studies have shown
Oliver, B, Oliver, B. Nigel
openaire   +1 more source

Fast calculation of two-electron-repulsion integrals: a numerical approach [PDF]

arXiv, 2016
An alternative methodology to evaluate two-electron-repulsion integrals based on numerical approximation is proposed. Computational chemistry has branched into two major fields with methodologies based on quantum mechanics and classical force fields. However, there are significant shadowy areas not covered by any of the available methods. Many relevant
arxiv