Results 121 to 130 of about 21,602 (293)
Cell Proliferation, EarlyView.Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li +10 more
wiley +1 more source
Clinical efficacy of reamberine in therapy for influenza
Терапевтический архив, 2010 Aim. To evaluate the tolerance and therapeutic effectiveness of 1.5% reamberine (RB) solution infusions in complex therapy for pneumonia-complicated pneumonia and acute respiratory diseases (ARD). Subjects and methods.
Valeriy Aleksandrovich Isakov +7 more
doaj
ONETEP + TOSCAM: uniting dynamical mean field theory and linear-scaling density functional theory [PDF]
arXiv, 2019 We introduce the unification of dynamical mean field theory (DMFT) and linear-scaling density functional theory (DFT), as recently implemented in ONETEP, a linear-scaling DFT package, and TOSCAM, a DMFT toolbox. This code can account for strongly correlated electronic behavior while simultaneously including the effects of the environment, making it ...
arxiv
Magnetic Relaxometry of Methemoglobin by Widefield Nitrogen-Vacancy Microscopy [PDF]
Appl. Phys. Lett. 125, 114002 (2024)Hemoglobin (Hb) is a multifaceted protein, classified as a metalloprotein, chromoprotein, and globulin. It incorporates iron, which plays a crucial role in transporting oxygen within red blood cells. Hb functions by carrying oxygen from the respiratory organs to diverse tissues in the body, where it releases oxygen to fuel aerobic respiration, thus ...
arxiv +1 more source
Aberrant Coordination Geometries Discovered in Most Abundant Metalloproteins [PDF]
, 2017 Metalloproteins play crucial biochemical roles in our body and are essential across all domains of life. The structural environment around a metal ion, especially the coordination geometry (CG), is both sequentially and functionally relevant.
Flight, Robert M. +3 more
core +1 more source
The FEBS Journal, Volume 292, Issue 8, Page 1950-1971, April 2025.This study identifies new senescent cell antiapoptotic pathways (SCAPs) by analyzing transcriptomic signatures and co‐expression networks. We uncover novel antiapoptotic pathways, called SCAPs, and propose potential senolytic drugs, including Fluorouracil, which targets key SCAPs.
Samael Olascoaga +6 more
wiley +1 more source
High-resolution electrochemical STM of redox metalloproteins [PDF]
, 2017 Electrochemical studies of redox active metalloproteins have become an increasingly fruitful area of study in recent years, particularly with the single-molecule resolution capability of electrochemical scanning tunnelling microscopy (EC-STM) which ...
Elliott, Martin
core +2 more sources
Metalloprotein-based electronic nanodevices [PDF]
, 2006 A key challenge of the current research in nanoelectronics is the realization of biomolecular devices. The use of electron-transfer proteins, such as the blue copper protein, azurin (Az), is particularly attractive because of its natural redox properties and self-assembly capability.
RINALDI, Rosaria +9 more
openaire +5 more sources
Experimental Physiology, EarlyView.Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto +10 more
wiley +1 more source
Dermatological Reviews, Volume 6, Issue 3, June 2025.ABSTRACT Background Skin disorders are highly common in type 1 and 2 diabetes mellitus patients. This study assessed the effects of a moisturizing formulation on photoprotected (volar forearm) and photoexposed (dorsal hand) skin in diabetic and nondiabetic participants, with or without stage I dermatoporosis, comparing it to a reference product ...
Juliana Rodrigues Pinto +2 more
wiley +1 more source